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Publication : Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids.

First Author  Lee F Year  1981
Journal  Nature Volume  294
Issue  5838 Pages  228-32
PubMed ID  6272123 Mgi Jnum  J:6641
Mgi Id  MGI:55115 Doi  10.1038/294228a0
Citation  Lee F, et al. (1981) Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids. Nature 294(5838):228-32
abstractText  Fusions between the mouse mammary tumour virus long terminal repeat and a mouse dihydrofolate reductase cDNA have been constructed in a SV40 vector. When these plasmids are transferred into recipient cells, the production of dihydrofolate reductase is regulated by glucocorticoid hormones. These results define a hormonally responsive region of the viral genome.
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