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Publication : Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome.

First Author  Leinwand LA Year  1983
Journal  Science Volume  221
Issue  4612 Pages  766-9
PubMed ID  6879174 Mgi Jnum  J:7154
Mgi Id  MGI:55625 Doi  10.1126/science.6879174
Citation  Leinwand LA, et al. (1983) Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome. Science 221(4612):766-9
abstractText  Cloned myosin heavy chain DNA probes from rat and human were hybridized to restriction endonuclease digests of genomic DNA from somatic cell hybrids and their parental cells. The mouse myosin heavy chain genes detectable by this assay were located on chromosome 11, and three different human sarcomeric myosin heavy chain genes were mapped to the short arm of chromosome 17. A synteny between myosin heavy chain and two unrelated markers, thymidine kinase and galactokinase, was found to be preserved in the rodent and human genomes.
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