First Author | Meruelo D | Year | 1977 |
Journal | J Exp Med | Volume | 146 |
Issue | 4 | Pages | 1079-87 |
PubMed ID | 197195 | Mgi Jnum | J:5863 |
Mgi Id | MGI:54340 | Doi | 10.1084/jem.146.4.1079 |
Citation | Meruelo D, et al. (1977) Genetic control of radiation leukemia virus-induced tumorigenesis. I. Role of the major murine histocompatibility complex, H-2. J Exp Med 146(4):1079-87 |
abstractText | Resistance to radiation leukemia virus-induced leukemogenesis is associated with the H-2D region of the H-2 complex, or with closely linked loci. The H-2Dd allele confers resistance ot the disease, while the H-2D-Q and H-2Ds alleles are associated with susceptibility. It is not clear whether Ir genes, or an alternative mechanism are responsible for the observed H-2-linked resistance to the disease. |