First Author | Otto J | Year | 1981 |
Journal | Biochem Genet | Volume | 19 |
Issue | 5-6 | Pages | 431-44 |
PubMed ID | 7028029 | Mgi Jnum | J:6619 |
Mgi Id | MGI:55094 | Doi | 10.1007/BF00484616 |
Citation | Otto J, et al. (1981) Prt-4 and Prt-5: new constituents of a gene cluster on chromosome 7 coding for esterproteases in the submandibular gland of the house mouse (Mus musculus). Biochem Genet 19(5-6):431-44 |
abstractText | The heredity and linkage of gene loci were established for two different enzymes with esterproteolytic activity from mouse submandibular gland: protease A and protease E. Based upon strain distribution and biochemical properties of the two esterproteases, the existence of two corresponding structural loci is proposed: Prt-4 (protease A) and Prt-5 (protease E). Prt-4 and Prt-5 proved to be different from Tam-1. From a four-point-cross, the gene order Gpi-1-(Tam-1, Prt-4, Prt-5)-c is suggested. Thus a gene cluster was shown to exist on chromosome 7 coding for esterproteases, all of which are controlled by testosterone. |