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Publication : Contributions of recent research to the classification of spontaneous lymphoid cell neoplasms in mice.

First Author  Pattengale PK Year  1986
Journal  Crit Rev Toxicol Volume  16
Issue  3 Pages  185-212
PubMed ID  2420529 Mgi Jnum  J:26474
Mgi Id  MGI:74760 Doi  10.3109/10408448609037464
Citation  Pattengale PK, et al. (1986) Contributions of recent research to the classification of spontaneous lymphoid cell neoplasms in mice [published erratum appears in CRC Crit Rev Toxicol 1986;17(2):183]. Crit Rev Toxicol 16(3):185-212
abstractText  The present review focuses on the mouse as an experimental immunopathologic model for non-Hodgkins' lymphomas and related leukemias. Immunomorphologic evidence will be presented which demonstrates that B and T cell subtypes of mouse lymphoid cell neoplasms resemble and are analogous to B and T cell subtypes of human lymphoid cell neoplasms. The many experimental advantages of the mouse system will be stressed with a particular emphasis on the concept that this newly defined immunomorphologic approach should be effectively combined with biologic, molecular, and cytogenetic parameters.
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