First Author | Pattengale PK | Year | 1986 |
Journal | Crit Rev Toxicol | Volume | 16 |
Issue | 3 | Pages | 185-212 |
PubMed ID | 2420529 | Mgi Jnum | J:26474 |
Mgi Id | MGI:74760 | Doi | 10.3109/10408448609037464 |
Citation | Pattengale PK, et al. (1986) Contributions of recent research to the classification of spontaneous lymphoid cell neoplasms in mice [published erratum appears in CRC Crit Rev Toxicol 1986;17(2):183]. Crit Rev Toxicol 16(3):185-212 |
abstractText | The present review focuses on the mouse as an experimental immunopathologic model for non-Hodgkins' lymphomas and related leukemias. Immunomorphologic evidence will be presented which demonstrates that B and T cell subtypes of mouse lymphoid cell neoplasms resemble and are analogous to B and T cell subtypes of human lymphoid cell neoplasms. The many experimental advantages of the mouse system will be stressed with a particular emphasis on the concept that this newly defined immunomorphologic approach should be effectively combined with biologic, molecular, and cytogenetic parameters. |