First Author | Leader DP | Year | 1985 |
Journal | Gene | Volume | 36 |
Issue | 3 | Pages | 369-74 |
PubMed ID | 3000889 | Mgi Jnum | J:15480 |
Mgi Id | MGI:63601 | Doi | 10.1016/0378-1119(85)90193-3 |
Citation | Leader DP, et al. (1985) The structure of a cloned mouse gamma-actin processed pseudogene. Gene 36(3):369-74 |
abstractText | The complete nucleotide (nt) sequence of a gamma-actin-like pseudogene (M gamma A-psi 1), isolated from a mouse genomic library in phage lambda, was determined. The pseudogene was shown to be of the processed type by the fact that it lacked introns, ended in a poly(dA) region, and was flanked by direct repeats. There were ten differences in the predicted amino acid (aa) sequence from that of the authentic nonmuscle gamma-actin. An unusual feature of M gamma A-psi 1 was the complete absence of DNA corresponding to the 5' end of the mRNA up to the nt preceding the Ala codon at aa position 7. This suggests that M gamma A-psi 1 originated from a truncated mRNA or from an incomplete reverse transcript. |