| First Author | Tait JF | Year | 1991 |
| Journal | Cytogenet Cell Genet | Volume | 57 |
| Issue | 4 | Pages | 187-92 |
| PubMed ID | 1683830 | Mgi Jnum | J:11551 |
| Mgi Id | MGI:59970 | Doi | 10.1159/000133143 |
| Citation | Tait JF, et al. (1991) Chromosomal localization of the human gene for annexin V (placental anticoagulant protein I) to 4q26----q28. Cytogenet Cell Genet 57(4):187-92 |
| abstractText | Annexin V is a member of a new family of calcium-dependent phospholipid-binding proteins. It has been previously isolated as placental anticoagulant protein I, inhibitor of blood coagulation, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4, and anchorin CII. The human gene encoding annexin V (ANX5) was localized to 4q26----q28 by in situ hybridization with a cDNA probe and polymerase chain-reaction (PCR) analysis of a human x hamster hybrid cell panel. The regional localization to 4q26----q28 was supported by Southern-blot analysis of a human cell line with a deletion in 4q23----q27. This localization overlaps but differs slightly from the previous assignment of ANX5 to 4q28----q32. Digestion with PvuII and TaqI identified polymorphisms at the ANX5 locus; the PvuII polymorphism could also be detected by PCR analysis. |
