| First Author | Konno R | Year | 1989 |
| Journal | Jpn J Genet | Volume | 64 |
| Issue | 5 | Pages | 341-5 |
| PubMed ID | 2576634 | Mgi Jnum | J:14917 |
| Mgi Id | MGI:63073 | Doi | 10.1266/jjg.64.341 |
| Citation | Konno R, et al. (1989) Linkage of the Dao-1 gene for D-amino-acid oxidase to the pgm-1 gene for phosphoglucomutase-1 on the mouse chromosome 5. Jpn J Genet 64(5):341-5 |
| abstractText | Linkage of the Dao-1 gene controlling D-amino-acid oxidase to the Pgm-1 gene controlling phosphoglucomutase-1 on the mouse chromosome 5 was examined. Mutant ddY/DAO- mice carrying a null Dao-1c allele had a Pgm-1a allele. Mutant mice were crossed to C3H/HeN and NZB/Kl mice carrying the Dao-1+ and Pgm-1b alleles. The hybrid F1 mice were backcrossed to the ddY/DAO- and their progeny were examined for alleles for D-amino-acid oxidase and phosphoglucomutase-1. In both backcrosses, the progeny with recombinant-type combinations of the alleles were significantly less than the progeny with the parental-type combinations, indicating the linkage of the Dao-1 and Pgm-1 genes. The recombination frequency between these loci was estimated to be 19.8 +/- 4.0%. |
