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Publication : Genetic studies on a major merozoite surface antigen of the malaria parasite of rodents, Plasmodium chabaudi.

First Author  McLean AP Year  1991
Journal  Parasite Immunol Volume  13
Issue  4 Pages  369-78
PubMed ID  1923562 Mgi Jnum  J:536
Mgi Id  MGI:49073 Doi  10.1111/j.1365-3024.1991.tb00290.x
Citation  McLean AP, et al. (1991) Genetic studies on a major merozoite surface antigen of the malaria parasite of rodents, Plasmodium chabaudi. Parasite Immunol 13(4):369-78
abstractText  Diversity in a major merozoite surface antigen (MSA-1) of Plasmodium chabaudi has been examined using a panel of monoclonal antibodies (MoAbs). The antigen was found to be different in each of twelve cloned isolates, as shown by its reactivity with the MoAbs in immunofluorescence tests. In genetic crossing experiments, the diverse forms of this antigen were shown to be determined by allelic variation of a single gene. Recombination occurred between the MSA-1 gene, a second blood stage antigen and enzyme markers.
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