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Publication : Gene for parathyroid hormone-like peptide is on mouse chromosome 6.

First Author  Hendy GN Year  1990
Journal  Cytogenet Cell Genet Volume  53
Issue  2-3 Pages  80-2
PubMed ID  1973379 Mgi Jnum  J:10623
Mgi Id  MGI:59071 Doi  10.1159/000132899
Citation  Hendy GN, et al. (1990) Gene for parathyroid hormone-like peptide is on mouse chromosome 6. Cytogenet Cell Genet 53(2-3):80-2
abstractText  The single-copy parathyroid hormone-like peptide gene (Pthlh) was assigned to mouse chromosome 6 using a rat PTHLH cDNA as hybridization probe in the Southern blot analysis of DNAs isolated from a panel of mouse x Chinese hamster cell hybrids. The mouse parathyroid hormone gene (Pth) has previously been assigned to mouse chromosome 7 and the PTHLH and PTH genes have also been shown to be on different chromosomes in human and rat. Therefore, despite significant amino-terminal sequence homology between the PTHLH and PTH peptides, as well as similarities in the structural organization of the human PTHLH and PTH genes, the genes encoding these peptides have discrete chromosomal locations in the mouse, rat, and man.
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