| First Author | Fan YS | Year | 1992 |
| Journal | Genomics | Volume | 14 |
| Issue | 4 | Pages | 1110-1 |
| PubMed ID | 1478654 | Mgi Jnum | J:3552 |
| Mgi Id | MGI:52064 | Doi | 10.1016/s0888-7543(05)80140-5 |
| Citation | Fan YS, et al. (1992) Localization of the human CYP17 gene (cytochrome P450(17 alpha)) to 10q24.3 by fluorescence in situ hybridization and simultaneous chromosome banding. Genomics 14(4):1110-1 |
| abstractText | The gene for human P450(17 alpha) (CYP17) was previously mapped to chromosome 10 through analysis of somatic cell hybrids. Using a modified procedure of fluorescence in situ hybridization, this gene has now been visualized on simultaneously banded chromosomes and localized to a specific subband of chromosome 10 at q24.3. This precise assignment may facilitate the understanding of the molecular basis of 17 alpha-hydroxylase/17,20-lyase deficiency and the evolution of the CYP superfamily of genes. |
