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Publication : An interspecific linkage map of mouse chromosome 15 positioned with respect to the centromere.

First Author  Brannan CI Year  1992
Journal  Genomics Volume  13
Issue  4 Pages  1075-81
PubMed ID  1354638 Mgi Jnum  J:1670
Mgi Id  MGI:50196 Doi  10.1016/0888-7543(92)90021-j
Citation  Brannan CI, et al. (1992) An interspecific linkage map of mouse chromosome 15 positioned with respect to the centromere. Genomics 13(4):1075-81
abstractText  We have used an interspecific backcross between C57BL/6J and Mus spretus to derive a molecular genetic linkage map of chromosome 15 that includes 25 molecular markers and spans 93% of the estimated length of chromosome 15. Using a second interspecific backcross that was analyzed with a centromere-specific marker, we were also able to position our map with respect to the chromosome 15 centromere. This map provides molecular access to many discrete regions on chromosome 15, thus providing a framework for establishing relationships between cloned DNA markers and known mouse mutations and for identifying homologous genes in mice and humans that may be involved in disease.
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