First Author | Safronova LD | Year | 1993 |
Journal | Genetika | Volume | 29 |
Issue | 12 | Pages | 1992-9 |
PubMed ID | 8119578 | Mgi Jnum | J:18203 |
Mgi Id | MGI:66214 | Citation | Safronova LD, et al. (1993) [Disturbance of the relationship of transmission in male mice carrying the translocation Rb(8,17)1 Iem in combination with t-haplotypes]. Genetika 29(12):1992-9 |
abstractText | t-complex typical feature of the house mouse 17th chromosome is the high transmission (up to 90-95%) of t-carrying chromosome to heterozygous +/t male offspring. The influence of Robertsonian translocation Rb1 (8, 17) Iem at t-haplotype transmission TRD level of heterozygotes Rb1+/+t6, Rb1+/+t12, Rb1+/+tw5, Rb1+/+tw18 in crossing with females of different genotypes was studied. Reliable decrease of TRD level in double heterozygotes of Rb1 and haplotypes t12, tw5, tw18 in comparison with the males ++/+t was discovered. For haplotype t6 no differences in TRD between Rb1+/+t6 and ++/+t6 were recorded. The cause of the obtained results is discussed. |