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Publication : Murine chromosomal location of four class III POU transcription factors.

First Author  Avraham KB Year  1993
Journal  Genomics Volume  18
Issue  1 Pages  131-3
PubMed ID  8276397 Mgi Jnum  J:15133
Mgi Id  MGI:63270 Doi  10.1006/geno.1993.1436
Citation  Avraham KB, et al. (1993) Murine chromosomal location of four class III POU transcription factors. Genomics 18(1):131-3
abstractText  A family of mouse genes encoding class III POU transcription factors consists of four members: Oct-6, Brn-2, Brn-1, and Brn-4. In accordance with mouse nomenclature, these loci have been designated Otf-6, Otf-7, Otf-8, and Otf-9, respectively. While the four genes share a highly conserved class III POU domain, the remaining regions are considerably diverged from each other. The POU domains of these transcription factors recognize the octamer-motif sequence and possess a similar DNA-binding specificity. Chromosomal mapping has demonstrated that the four genes are unlinked: Otf-6 is located on the distal region of chromosome 4, Otf-7 on the proximal region of chromosome 4, Otf-8 on chromosome 1, and Otf-9 on the X chromosome.
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