| First Author | Kozak CA | Year | 1995 |
| Journal | Genomics | Volume | 29 |
| Issue | 1 | Pages | 294-6 |
| PubMed ID | 8530091 | Mgi Jnum | J:28836 |
| Mgi Id | MGI:76375 | Doi | 10.1006/geno.1995.1250 |
| Citation | Kozak CA, et al. (1995) Mapping of the mouse macrophage inflammatory protein-1 alpha receptor gene Scya3r and two related mouse beta chemokine receptor-like genes to chromosome 9. Genomics 29(1):294-6 |
| abstractText | Macrophage inflammatory protein-1 alpha (MIP-1 alpha) and RANTES are members of the beta chemokine family of leukocyte chemoattractants. We have previously cloned three mouse genes by cross-hybridization with the human MIP-1 alpha/RANTES receptor gene CMKBR1. One of the mouse genes, Scya3r, encodes a functional MIP-1 alpha receptor. The functions of the other two, Scya3r-rs1 and Scya3r-rs2, are not known. We have now mapped Scya3r, Scya3r-rs1, and Scya3r-rs2 to chromosome 9, in a region of conserved synteny with the location of CMKBR1. Thus, like chemokine genes and alpha chemokine receptor genes, this group of beta chemokine receptor genes arose by tandem duplication. |
