| First Author | Inumaru S | Year | 1995 |
| Journal | Immunol Cell Biol | Volume | 73 |
| Issue | 5 | Pages | 474-6 |
| PubMed ID | 8595928 | Mgi Jnum | J:29685 |
| Mgi Id | MGI:77210 | Doi | 10.1038/icb.1995.74 |
| Citation | Inumaru S, et al. (1995) cDNA cloning of porcine granulocyte-macrophage colony-stimulating factor. Immunol Cell Biol 73(5):474-6 |
| abstractText | Porcine granulocyte-macrophage colony-stimulating factor (GM-CSF) cDNA was cloned by using polymerase chain reaction (PCR) and sequenced. A coding sequence of the porcine GM-CSF precursor protein, including the signal peptide sequence and stop codon, is 435 bp in length. The identities of the porcine GM-CSF coding sequence when compared to ovine, bovine, human and murine sequences were 89, 86, 83 and 70% at the nucleotide level, and 80, 74, 73, and 56% at the amino acid level. The hydrophobicity profiles, putative glycosylation sites and positions of cysteine residues were highly conserved in porcine, ovine, bovine and human GM-CSF but not murine. This is the first report of the porcine GM-CSF cDNA cloning and sequence. |
