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Publication : Vertebrate heart development.

First Author  Lyons GE Year  1996
Journal  Curr Opin Genet Dev Volume  6
Issue  4 Pages  454-60
PubMed ID  8791539 Mgi Jnum  J:34948
Mgi Id  MGI:82403 Doi  10.1016/s0959-437x(96)80067-0
Citation  Lyons GE (1996) Vertebrate heart development. Curr Opin Genet Dev 6(4):454-60
abstractText  This review summarizes recent studies of the cellular and molecular events involved in the determination and differentiation of cardiac myocytes in vertebrate embryos. Fate-mapping studies in mouse, chick, amphibian and zebrafish embryos suggest that cardiac muscle precursors are specified shortly before or at the time of gastrulation. Nuclear factors, such as dHAND, aryl hydrocarbon receptor, GATA-6, Nkx-2.3, growth arrest homeobox (Gax) and cardiac adriamycin responsive protein (CARP), which have recently been described as playing a role in the commitment and/or differentiation of cardiac myocytes are discussed.
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