| First Author | Wise LD | Year | 1997 |
| Journal | Teratology | Volume | 55 |
| Issue | 4 | Pages | 249-92 |
| PubMed ID | 9216042 | Mgi Jnum | J:41345 |
| Mgi Id | MGI:893789 | Doi | 10.1002/(SICI)1096-9926(199704)55:4<249::AID-TERA5>3.0.CO;2-W |
| Citation | Wise LD, et al. (1997) Terminology of developmental abnormalities in common laboratory mammals (version 1). Teratology 55(4):249-92 |
| abstractText | This paper presents the first version of an internationally-developed glossary of terms for structural developmental abnormalities in common laboratory animals. The glossary is put forward by the International Federation of Teratology Societies (IFTS) Committee on International Harmonization of Nomenclature in Developmental Toxicology, and represents considerable progress toward harmonization of terminology in this area. The purpose of this effort is to provide a common vocabulary that will reduce confusion and ambiguity in the description of developmental effects, particularly in submissions to regulatory agencies worldwide. The glossary contains a primary term or phrase, a definition of the abnormality, and notes, where appropriate. Selected synonyms or related terms, which reflect a similar or closely related concept, are noted. Nonpreferred terms are indicated where their usage may be incorrect. Modifying terms used repeatedly in the glossary (e.g., absent, branched) are listed and defined separately, instead of repeating their definitions for each observation. Syndrome names are generally excluded from the glossary, but are listed separately in an appendix. The glossary is organized into broad sections for external, visceral, and skeletal observations, then subdivided into regions, structures, or organs in a general overall head to tail sequence. Numbering is sequential, and not in any regional or hierarchical order. Uses and misuses of the glossary are discussed. Comments, questions, suggestions, and additions from practitioners in the field of developmental toxicology are welcomed on the organization of the glossary as well as on the specific terms and definitions. Updates of the glossary are planned based on the comments received. |
