| First Author | Espinosa L | Year | 1997 |
| Journal | Biochim Biophys Acta | Volume | 1354 |
| Issue | 1 | Pages | 58-64 |
| PubMed ID | 9375793 | Mgi Jnum | J:44030 |
| Mgi Id | MGI:1099281 | Doi | 10.1016/s0167-4781(97)00124-3 |
| Citation | Espinosa L, et al. (1997) Primary sequence of the human, lysine-rich, ribosomal protein RPL38 and detection of an unusual RPL38 processed pseudogene in the promoter region of the type-1 angiotensin II receptor gene. Biochim Biophys Acta 1354(1):58-64 |
| abstractText | We have isolated a cDNA clone encoding the human ribosomal protein L38 (HSRPL38). The longest ORF of the cDNA predicts a lysine-rich small polypeptide identical to the rat RPL38 protein (100% identity), and sharing a 84% of identity to the tomato RPL38 protein sequence. Northern blot analysis of a number of epithelial cell lines showed that the HSRPL38 is encoded by a mRNA ubiquitously expressed. Southern blot analysis of human genomic DNA suggested that the RPL38 does not constitute a multigene family but it is encoded by a reduced set of active genes, among which we have also found a RPL38 processed pseudogene located in the promoter region of the human type-1 angiotensin II receptor gene. This RPL38 pseudogene is very unusual among processed pseudogenes in that the poly A tail and the entire 5'-UTR of the original RPL38 mRNA were deleted during the retrotransposition process. |
