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Publication : Expression of Ly-6C on microglia in the developing and adult mouse brain.

First Author  Tanaka M Year  1997
Journal  Neurosci Lett Volume  239
Issue  1 Pages  17-20
PubMed ID  9547161 Mgi Jnum  J:45855
Mgi Id  MGI:1196195 Doi  10.1016/s0304-3940(97)00878-1
Citation  Tanaka M, et al. (1997) Expression of Ly-6C on microglia in the developing and adult mouse brain. Neurosci Lett 239(1):17-20
abstractText  Expression of Ly-6C, a murine homolog of human CD59, in the brain was examined immunologically using an ER-MP20 monoclonal antibody both in vitro and in vivo. Ly-6C was expressed both on the isolated microglia and on microglia in the developing and adult cerebellum. The number of cerebellar microglia expressing Ly-6C markedly increased during the first postnatal week in mouse development. The expression of Ly-6C on microglia in the developing and adult brain may be related to the unique role(s) of microglia under normal and/or pathological conditions of the brain.
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