| First Author | Rice OV | Year | 2002 |
| Journal | Brain Res | Volume | 945 |
| Issue | 1 | Pages | 135-8 |
| PubMed ID | 12113961 | Mgi Jnum | J:81279 |
| Mgi Id | MGI:2448767 | Doi | 10.1016/s0006-8993(02)02890-1 |
| Citation | Rice OV, et al. (2002) Conditioned place preference to morphine in cannabinoid CB1 receptor knockout mice. Brain Res 945(1):135-8 |
| abstractText | Recent reports have suggested an involvement of the brain cannabinoid system in the morphine-reward pathway. To address this question we evaluated whether CB1 receptor knockout mice would show a conditioned place preference to morphine. CB1 receptor knockout mice developed a strong place preference to 4 and 8 mg/kg morphine, similar to that in wild-type Swiss-Webster mice. This data thus does not support a contribution of the brain cannabinoid system to morphine reward. |
