| Type | MGI:General | Description | mice exhibit a severe increase in central nuclei (in greater than 25% of fibers), atrophic fibers, ring fibers, and sarcoplasmic masses muscle fiber cross-section area is increased (2710+/-550 um2 compared to 1849+/-329 um2 in Tg(HSA*SR)29Cath mice) muscle nuclei per muscle fiber is increased (2.9+/-0.7 compared to 0.8+/-0.14 in Tg(HSA*SR)29Cath mice) the number of muscle nuclei per fiber cross-section area is increased (1100+/-400 mm2 compared to 450+/-40 mm2 in Tg(HSA*SR)29Cath mice) the percentage of muscle nuclei that are central is increased (38+/-0.09% compared to 1.4+/-0.6% in Tg(HSA*SR)29Cath mice) |