| Type | MGI:General | Description | intranuclear inclusions are detected in the cytoplasm of cortical neurons and to a lesser degree in striatal neurons in a sample of five mice, 27-70% of large striatal neurons that labeled for huntingtin had inclusions nuclear inclusions are composed of granules and filaments as determined by electron microscopy in 11 of 14 mice, inclusions appeared in a few cells in the hippocampus, substantia nigra, cerebellum and brainstem |
