| Type | MGI:General | Description | the majority of lymphomas are diffuse large-cell lymphoma with B-cell origins or indeterminate origin some cases present a polymorphic cytology consisting of a heterogeneous mixture of small and large lymphocytes B cells lacking IgM expression constitute the majority of the large cells in the cases of disseminated disease Ig-heavy chain analysis of lymphomas reveals clonal rearrangement of the immunoglobulin heavy-chain locus (except in the one case of T cell lymphoma) demonstrating a B cell origin |