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Comment :

Type  MGI:General Description  mammary tumors in chronically doxycycline induced females are invasive mammary adenocarcinomas withdrawal of doxycycline from chronically induced tumor-bearing mutants results in rapid regression of a subset of invasive mammary adenocarcinomas (14 days) but another subset of tumors decrease in size but then resume growth tumors that continue to grow after doxycycline removal show undetectable expression of the MYC transgene but increased endogenous Myc expression and exhibit mutations in Kras or Nras