| Type | MGI:General | Description | mice exhibit progressive liver lesions that begin after 2 months of age with karyomegaly and cytomegaly of hepatocytes at 7 to 8 months of age, mice exhibit foci's heterogeneity of cell size and cellular dysplasia in the liver mice exhibit single to multiple foci liver nodules of 0.5 cm in diameter or greater liver lesions develop in a progressive fashion, with neoplasia confirmed at autopsy |