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Comment :

Type  MGI:General Description  astrocytes from amygdala and substantia nigra show frequent invaginations of the nuclear envelope which are rarely seen in wild-type mice and exhibit abnormal mitochondria astrocytes exhibit abundant pleiomoprhic, osmiophilic inclusions and lipofuscin granules, features of macroautophagy and show accumulation of iron-laden intracellular inclusions