| Type | MGI:General | Description | at 18 months, mice exhibit age-dependent, vasculature-associated Dan-amyloid deposition in the amygdala, thalamus, brainstem, and cerebellum unlike wild-type mice smaller vessels are often obstructed by depositions perivascular plaques often surround a significant portion of the vessel surface perivascular amyloid penetrates into the surrounding parenchyma and is surrounded by microglia and dystrophic neurites |