| Type | MGI:General | Description | in the open-field water maze, mice show increased path length to find the hidden platform at 6 and 12 months of age, indicating decreased spatial precision in the open-field water maze, mutants show about 50% reduction in directed swims and a modest decrease of focal searches, are slower to abstain from wall hugging and maintain scanning, and have a high percentage (about 35%) of chaining responses to solve the task |