| Type | MGI:General | Description | mice exhibit upregulation of autophagy marker proteins Map1lc3a (LC3-II) and beclin 1, and reduced protein levels of small heat shock proteins Cryab and Hspb1 indicating enhanced BAG3-activated autophagy system mice treated with chloroquine, an inhibitor of the autophagy system, show recovery of Cryab and Hspb1 protein levels and exhibit autophagosomes and autolysosome-like structures in heart ventricles which are not seen in controls |
