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Comment :

Type  MGI:General Description  proportion of myocyte nuclei with tubulo-filamentous ultrastructures and containing KCl-insoluble aggregates increases with age, compared to nontransgenic controls mutants have increased numbers of apoptotic myocyte nuclei compared to controls at 6-12 months musle has increased numbers vacuoules aggregate formation is decreased with DOX treatment and number of apoptotic nuclei is reduced