| Type | MGI:General | Description | mice show impairments on the rotarod starting at 20 weeks of age and by 40 weeks, show dramatic deterioration in performance on both the accelerating and constant speed rods chronic treatment with 17-DMAG delays the motor deficits in the rotarod, motor swimming, and balance beam test by about 8 weeks, however treatment does not affect weakness/hyponia, tremors and abnormal reflexes |
