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Comment :

Type  MGI:General Description  mice show progressive loss of enteric neurons enteric neuron loss is predominantly of Nos1 expressing (inhibitory motor fibers) ganglion cell bodies that do not exhibit Atxn7-positive inclusions residual Nos1+ neurons have enlarged cell bodies and some of their axons are unusually thick and tortuous with abnormal varicosities calretinin-immunoreactive neurons in myenteric ganglia are reduced in density