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Comment :

Type  MGI:General Description  SARS-CoV-infected mice develop a strong inflammatory cytokine reaction that occurs later and more intensely in the brain than in the lungs SARS-CoV-infected mice show elevated levels of IL-1beta, IL-12p40, IL-12p70, CXCL1, RANTES, and MCP-1 in the lungs, elevated levels of IL-6, IL-12p40, G-CSF, CXCL1, MIP-1alpha, and MCP-1 in the brains and increased secretion of IL-1alpha, IL-1beta, GM-CSF, IL-12p70 and RANTES in the brain