| Type | MGI:General | Description | mice exhibit preexcitation unlike in wild-type mice early doxycycline treatment (prenatally to 8 weeks of age) delays myocardial dysfunction doxycycline-treatment between 4 and 16 weeks results in a decline of preexcitation from 50% to 11% and is accompanied by atrial pacing doxycycline treatment after 8 weeks does not cause loss of preexcitation or alter the electrical properties of accessory pathways |