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Publication : T1Wh, a promising mouse strain with chromosomal markers for cleft palate research.

First Author  Miller KK Year  1977
Journal  Teratology Volume  16
Issue  1 Pages  41-6
PubMed ID  898090 Mgi Jnum  J:156164
Mgi Id  MGI:4418832 Doi  10.1002/tera.1420160107
Citation  Miller KK, et al. (1977) T1Wh, a promising mouse strain with chromosomal markers for cleft palate research. Teratology 16(1):41-6
abstractText  Attainment of the horizontal position by the secondary palatal shelves and fusion in relationship to morphological and chronological ages in T1Wh, and albino strain of mice homozygous for a 5;19 Robertsonian translocation, was found to be late and slow in comparison to other strains previously investigated. Spontaneous and cortisone-induced cleft palate frequencies of 3.5% and 100% respectively, were found in this strain. Its slow and late palatal closure, high susceptibility to cortisone, obvious marker chromosomes, and good breeding performance promise to make T1Wh a useful strain for cleft palate research.
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