First Author | Miller KK | Year | 1977 |
Journal | Teratology | Volume | 16 |
Issue | 1 | Pages | 41-6 |
PubMed ID | 898090 | Mgi Jnum | J:156164 |
Mgi Id | MGI:4418832 | Doi | 10.1002/tera.1420160107 |
Citation | Miller KK, et al. (1977) T1Wh, a promising mouse strain with chromosomal markers for cleft palate research. Teratology 16(1):41-6 |
abstractText | Attainment of the horizontal position by the secondary palatal shelves and fusion in relationship to morphological and chronological ages in T1Wh, and albino strain of mice homozygous for a 5;19 Robertsonian translocation, was found to be late and slow in comparison to other strains previously investigated. Spontaneous and cortisone-induced cleft palate frequencies of 3.5% and 100% respectively, were found in this strain. Its slow and late palatal closure, high susceptibility to cortisone, obvious marker chromosomes, and good breeding performance promise to make T1Wh a useful strain for cleft palate research. |