| First Author | Marschall HU | Year | 2010 |
| Journal | Biochem Biophys Res Commun | Volume | 396 |
| Issue | 1 | Pages | 58-62 |
| PubMed ID | 20494111 | Mgi Jnum | J:160599 |
| Mgi Id | MGI:4454710 | Doi | 10.1016/j.bbrc.2010.02.143 |
| Citation | Marschall HU, et al. (2010) The genetic background of gallstone formation: an update. Biochem Biophys Res Commun 396(1):58-62 |
| abstractText | Gallstone disease is one of the most prevalent gastrointestinal diseases with a substantial burden to health care systems that is expected to increase in ageing populations at risk. This review summarizes recent data on the genetic background of cholesterol gallstones and the role of biliary lipid composition. Three previously unknown non-synonymous mutations in the ABCB4 gene encoding the hepatobiliary phospholipid-flippase MDR3 are presented. |
