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Publication : A YY1 bridge for X inactivation.

First Author  Thorvaldsen JL Year  2011
Journal  Cell Volume  146
Issue  1 Pages  11-3
PubMed ID  21729777 Mgi Jnum  J:174281
Mgi Id  MGI:5056219 Doi  10.1016/j.cell.2011.06.029
Citation  Thorvaldsen JL, et al. (2011) A YY1 Bridge for X Inactivation. Cell 146(1):11-3
abstractText  Xist RNA inactivates one mammalian X chromosome (the Xi) by associating with it in cis. The mechanism of this interaction is unresolved. Jeon and Lee (2011) now show that YY1 binds both Xist RNA and DNA, thereby providing a mechanism to anchor Xist to the Xi and facilitate X chromosome inactivation.
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