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Publication : Autophagy-mediated tumor promotion.

First Author  Guo JY Year  2013
Journal  Cell Volume  155
Issue  6 Pages  1216-9
PubMed ID  24315093 Mgi Jnum  J:205259
Mgi Id  MGI:5544496 Doi  10.1016/j.cell.2013.11.019
Citation  Guo JY, et al. (2013) Autophagy-mediated tumor promotion. Cell 155(6):1216-9
abstractText  Mouse models for cancer are revealing novel cancer-promoting roles for autophagy. Autophagy promotes tumor growth by suppressing the p53 response, maintaining mitochondrial function, sustaining metabolic homeostasis and survival in stress, and preventing diversion of tumor progression to benign oncocytomas.
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