| First Author | Buhusi M | Year | 2017 |
| Journal | Behav Brain Res | Volume | 324 |
| Pages | 96-99 | PubMed ID | 28212945 |
| Mgi Jnum | J:249649 | Mgi Id | MGI:5920922 |
| Doi | 10.1016/j.bbr.2017.02.023 | Citation | Buhusi M, et al. (2017) Sex differences in interval timing and attention to time in C57Bl/6J mice. Behav Brain Res 324:96-99 |
| abstractText | Interval timing is crucial for decision-making and motor control and is impaired in many neuropsychiatric disorders. Previous studies examined timing in various strains or genetically-altered mice, but not in parallel in male and female mice in the same experimental setting. We investigated timing and attention to time in male and female C57Bl/6J mice, when presented with gaps in the timed stimulus, novel auditory distracters presented during the un-interrupted timed stimulus, and gap+distracter combinations. No sex differences were found in regard to timing accuracy and precision. However, presentation of the gap+distracter combination over-reset timing in males but had a much smaller effect in females. The over-reset strategy was reported previously with emotional distracters (e.g., previously paired with footshock) but not with neutral distracters. These results reveal sex differences in attentional gating/switching or working memory for time. |
