| First Author | Bishop CE | Year | 1988 |
| Journal | Philos Trans R Soc Lond B Biol Sci | Volume | 322 |
| Issue | 1208 | Pages | 119-24 |
| PubMed ID | 2907795 | Mgi Jnum | J:34256 |
| Mgi Id | MGI:81721 | Doi | 10.1098/rstb.1988.0119 |
| Citation | Bishop CE, et al. (1988) Molecular aspects of sex determination in mice: an alternative model for the origin of the Sxr region. Philos Trans R Soc Lond B Biol Sci 322(1208):119-24 |
| abstractText | Using a combination of in situ mapping and DNA analysis with recombinant DNA probes specific for the Sxr region of the mouse Y chromosome, we show that both the gene(s) controlling primary sex determination and the expression of the male-specific antigen H-Y (Tdy and Hya respectively) are located on the minute short arm of the mouse Y chromosome. We demonstrate that the H-Y- variant of Sxr (Sxr') arose by a partial deletion within the Sxr region and propose an alternative model for the generation of the original Sxr region. |