| First Author | Ishikawa M | Year | 2003 |
| Journal | Brain Res | Volume | 976 |
| Issue | 2 | Pages | 262-3 |
| PubMed ID | 12763262 | Mgi Jnum | J:83812 |
| Mgi Id | MGI:2663591 | Doi | 10.1016/s0006-8993(03)02654-4 |
| Citation | Ishikawa M, et al. (2003) N(2)O stimulates NOS enzyme activity in C57BL/6 but not DBA/2 mice. Brain Res 976(2):262-3 |
| abstractText | Exposure to 70% N(2)O produces a prominent antinociception in C57BL/6 mice but not DBA/2 mice. N(2)O exposure also increases conversion of [14C]L-arginine to [14C]L-citrulline in homogenates prepared from whole brains of C57BL/6 mice; there was no such increase in NOS activity in the DBA/2 whole brain. A differential N(2)O effect on brain NOS in these inbred strains might explain why the C57BL/6 but not DBA/2 mice are responsive to N(2)O antinociception. |
