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Publication : Leukemogenicity of the AKXD strains

First Author  Mucenski M Year  1986
Journal  Mouse News Lett Volume  74
Pages  88 Mgi Jnum  J:24745
Mgi Id  MGI:72474 Citation  Mucenski M, et al. (1986) Leukemogenicity of the AKXD strains. Mouse News Lett 74:88
abstractText  Full text of MNL contribution: 6. Leukemogenicity of the AKXD Strains. Research involves the use of molecular genetics to study murine lymphoid neoplasms. Twenty-four AKXD recombinant inbred mouse strains (derived from AKR/J, a highly lymphomatous strain, and DBA/2J, a weakly lymphomatous strain) are being analyzed for somatically-acquired proviruses. This is being done in an attempt to identify common sites of viral integration. An objective of this work is to identify proto-oncogenes as well as new cellular oncogenes that may be activated by viral integration and play a role in lymphoma development. (Mucenski, Gilbert).
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