First Author | Mucenski M | Year | 1986 |
Journal | Mouse News Lett | Volume | 74 |
Pages | 88 | Mgi Jnum | J:24745 |
Mgi Id | MGI:72474 | Citation | Mucenski M, et al. (1986) Leukemogenicity of the AKXD strains. Mouse News Lett 74:88 |
abstractText | Full text of MNL contribution: 6. Leukemogenicity of the AKXD Strains. Research involves the use of molecular genetics to study murine lymphoid neoplasms. Twenty-four AKXD recombinant inbred mouse strains (derived from AKR/J, a highly lymphomatous strain, and DBA/2J, a weakly lymphomatous strain) are being analyzed for somatically-acquired proviruses. This is being done in an attempt to identify common sites of viral integration. An objective of this work is to identify proto-oncogenes as well as new cellular oncogenes that may be activated by viral integration and play a role in lymphoma development. (Mucenski, Gilbert). |