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Search results 201 to 222 out of 222 for Cd70

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0.028s

Type

Details

Score

Publication

22628427 | J:189295

First Author:	Claus C
Year:	2012
Journal:	Cancer Res
Title:	CD27 signaling increases the frequency of regulatory T cells and promotes tumor growth.
Volume:	72
Issue:	14
Pages:	3664-76

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Publication

21763160 | J:174514

First Author:	van Gisbergen KP
Year:	2011
Journal:	Immunity
Title:	The costimulatory molecule CD27 maintains clonally diverse CD8(+) T cell responses of low antigen affinity to protect against viral variants.
Volume:	35
Issue:	1
Pages:	97-108

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Publication

23263849 | -

First Author:	Kamazani FM
Year:	2013
Journal:	Med Oncol
Title:	CD44 and CD27 expression pattern in B cell precursor acute lymphoblastic leukemia and its clinical significance.
Volume:	30
Issue:	1
Pages:	359

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Publication

20699361 | -

First Author:	Denoeud J
Year:	2011
Journal:	J Leukoc Biol
Title:	Role of CD27/CD70 pathway of activation in immunity and tolerance.
Volume:	89
Issue:	2
Pages:	195-203

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Protein Domain

IPR034000 | TNFRSF7_N

Type:

Domain

Description:

Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), also known as CD27, T14, S152, Tp55, S152 or LPFS2, has a key role in the generation of immunological memory via effects on T-cell expansion and survival, and B cell development [, ]. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK, and mediates the signaling process through adaptor proteins TRAF2 and TRAF5. CD27-binding protein (SIVA), a pro-apoptotic protein, can bind to CD27 and may play an important role in the apoptosis induced by this receptor []. The potential role of the CD27/CD70 pathway in the course of inflammatory diseases, such as arthritis, and inflammatory bowel disease, suggests that CD70 may be a target for immune intervention. The expression of CD27 and CD44 molecules correlates with the differentiation stage of B cell precursors and has been shown to have a biological significance in acute lymphoblastic leukemia [].This entry represents the N-terminal domain of TNFRSF7. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].

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Publication

15004164 | J:88620

First Author:	Nolte MA
Year:	2004
Journal:	J Immunol
Title:	B cells are crucial for both development and maintenance of the splenic marginal zone.
Volume:	172
Issue:	6
Pages:	3620-7

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Publication

15187121 | J:90837

First Author:	Xiao Y
Year:	2004
Journal:	J Immunol
Title:	CD27 is acquired by primed B cells at the centroblast stage and promotes germinal center formation.
Volume:	172
Issue:	12
Pages:	7432-41

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Publication

20140903 | J:159189

First Author:	De Colvenaer V
Year:	2010
Journal:	Eur J Immunol
Title:	Continuous CD27 triggering in vivo strongly reduces NK cell numbers.
Volume:	40
Issue:	4
Pages:	1107-17

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Publication

20008292 | J:159408

First Author:	Chan CJ
Year:	2010
Journal:	J Immunol
Title:	DNAM-1/CD155 interactions promote cytokine and NK cell-mediated suppression of poorly immunogenic melanoma metastases.
Volume:	184
Issue:	2
Pages:	902-11

•

Publication

16231287 | J:113775

First Author:	Matter M
Year:	2005
Journal:	Eur J Immunol
Title:	Virus-induced polyclonal B cell activation improves protective CTL memory via retained CD27 expression on memory CTL.
Volume:	35
Issue:	11
Pages:	3229-39

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Publication

21048108 | J:166131

First Author:	Peperzak V
Year:	2010
Journal:	J Immunol
Title:	The Pim kinase pathway contributes to survival signaling in primed CD8+ T cells upon CD27 costimulation.
Volume:	185
Issue:	11
Pages:	6670-8

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Publication

22232214 | J:184503

First Author:	Schürch C
Year:	2012
Journal:	J Clin Invest
Title:	CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progression.
Volume:	122
Issue:	2
Pages:	624-38

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Publication

18523434 | J:174339

First Author:	Sawalha AH
Year:	2008
Journal:	Genes Immun
Title:	Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients.
Volume:	9
Issue:	4
Pages:	368-78

•

Publication

23447580 | J:197055

First Author:	Fu L
Year:	2013
Journal:	Cancer Res
Title:	Activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis.
Volume:	73
Issue:	9
Pages:	2916-25

•

Publication

31393597 | J:281758

First Author:	Bialojan A
Year:	2019
Journal:	Eur J Immunol
Title:	Transcutaneous immunization with CD40 ligation boosts cytotoxic T lymphocyte mediated antitumor immunity independent of CD4 helper cells in mice.
Volume:	49
Issue:	11
Pages:	2083-2094

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Publication

33361812 | J:305919

First Author:	Choi IK
Year:	2021
Journal:	Nature
Title:	Mechanism of EBV inducing anti-tumour immunity and its therapeutic use.
Volume:	590
Issue:	7844
Pages:	157-162

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Protein

P41272

Organism:	Mus musculus/domesticus
Length:	250
Fragment?:	false

•

Publication

9177220 | J:117434

First Author:	Prasad KV
Year:	1997
Journal:	Proc Natl Acad Sci U S A
Title:	CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein.
Volume:	94
Issue:	12
Pages:	6346-51

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Protein

Q3U4X0

Organism:	Mus musculus/domesticus
Length:	250
Fragment?:	false

•

Publication

9538693 | -

First Author:	Naismith JH
Year:	1998
Journal:	Trends Biochem Sci
Title:	Modularity in the TNF-receptor family.
Volume:	23
Issue:	2
Pages:	74-9

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Publication

11796220 | -

First Author:	Bodmer JL
Year:	2002
Journal:	Trends Biochem Sci
Title:	The molecular architecture of the TNF superfamily.
Volume:	27
Issue:	1
Pages:	19-26

•

Publication

8387891 | -

First Author:	Banner DW
Year:	1993
Journal:	Cell
Title:	Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation.
Volume:	73
Issue:	3
Pages:	431-45

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