Type |
Details |
Score |
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Mouse Synonym Curation |
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Publication |
First Author: |
Gray PA |
Year: |
2004 |
Journal: |
Science |
Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
Volume: |
306 |
Issue: |
5705 |
Pages: |
2255-7 |
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•
•
•
•
•
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Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
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•
•
•
•
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Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
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•
•
•
•
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Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
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•
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Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
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•
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Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
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•
•
•
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Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
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Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
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•
•
•
•
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Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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•
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•
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•
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Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
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•
•
•
•
•
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Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
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•
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Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
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•
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Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
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•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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•
•
•
•
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Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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•
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Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
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•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
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Publication |
First Author: |
Fu C |
Year: |
2020 |
Journal: |
J Biol Chem |
Title: |
The transcription factor ZFHX3 is crucial for the angiogenic function of hypoxia-inducible factor 1α in liver cancer cells. |
Volume: |
295 |
Issue: |
20 |
Pages: |
7060-7074 |
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HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
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Allele |
Name: |
zinc finger homeobox 3; short circuit |
Allele Type: |
Chemically induced (ENU) |
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Strain |
Attribute String: |
congenic, chemically induced mutation, mutant strain |
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•
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•
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Genotype |
Symbol: |
Zfhx3/Zfhx3 |
Background: |
involves: BALB/cOlaHsd * C3H/HeH * C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
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•
•
•
•
•
|
Genotype |
Symbol: |
Zfhx3/Zfhx3<+> |
Background: |
involves: BALB/cOlaHsd * C3H/HeH |
Zygosity: |
ht |
Has Mutant Allele: |
true |
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•
•
•
•
•
|
Genotype |
Symbol: |
Per2/Per2<+> Zfhx3/Zfhx3<+> |
Background: |
involves: 129S6/SvEvTac * BALB/cOlaHsd * C3H/HeH * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Publication |
First Author: |
Chung CD |
Year: |
1997 |
Journal: |
Science |
Title: |
Specific inhibition of Stat3 signal transduction by PIAS3. |
Volume: |
278 |
Issue: |
5344 |
Pages: |
1803-5 |
|
•
•
•
•
•
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Publication |
First Author: |
Rödel B |
Year: |
2000 |
Journal: |
EMBO J |
Title: |
The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3. |
Volume: |
19 |
Issue: |
21 |
Pages: |
5845-55 |
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•
•
•
•
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Publication |
First Author: |
Levy C |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
A new role for the STAT3 inhibitor, PIAS3: a repressor of microphthalmia transcription factor. |
Volume: |
277 |
Issue: |
3 |
Pages: |
1962-6 |
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•
•
•
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
75
 |
Fragment?: |
true |
|
•
•
•
•
•
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Publication |
First Author: |
Park JH |
Year: |
2014 |
Journal: |
Nat Commun |
Title: |
Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage. |
Volume: |
5 |
|
Pages: |
5483 |
|
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•
•
•
•
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Publication |
First Author: |
Sun X |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Characterization of nuclear localization and SUMOylation of the ATBF1 transcription factor in epithelial cells. |
Volume: |
9 |
Issue: |
3 |
Pages: |
e92746 |
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•
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Protein Domain |
Type: |
Family |
Description: |
PIAS3 is an E3-type small ubiquitin-like modifier (SUMO) ligases, stabilising the interaction between UBE2I and Ubc9 respectively and the substrate, and as a SUMO-tethering factor. It plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway [, , , ].PIAS3 sumoylates CCAR2, promoting its interaction with SIRT1 []and diminishes the sumoylation of ZFHX3 by preventing the colocalization of ZFHX3 with SUMO1 in the nucleus [].SUMO proteins are ubiquitin like proteins that are covalently attached to and detached from other proteins in cells to modify their function. SUMO is first activated in an ATP-dependent reaction by formation of a thioester bond with an E1 (SUMO-activating) enzyme and then transferred to the SUMO conjugating (E2) enzyme Ubc9. Ubc9 catalyses the formation of an isopeptide bond between the C-terminal of SUMO and the amino group of lysine in the target protein. Sumoylated proteins can be targeted for different cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability []. |
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•
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Publication |
First Author: |
Duval D |
Year: |
2003 |
Journal: |
FEBS Lett |
Title: |
The 'PINIT' motif, of a newly identified conserved domain of the PIAS protein family, is essential for nuclear retention of PIAS3L. |
Volume: |
554 |
Issue: |
1-2 |
Pages: |
111-8 |
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•
•
•
•
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Publication |
First Author: |
Lozano-Velasco E |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
Hyperthyroidism, but not hypertension, impairs PITX2 expression leading to Wnt-microRNA-ion channel remodeling. |
Volume: |
12 |
Issue: |
12 |
Pages: |
e0188473 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
52
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
90
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
385
 |
Fragment?: |
true |
|
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•
•
•
•
|
Publication |
First Author: |
Su HL |
Year: |
2002 |
Journal: |
Gene |
Title: |
Molecular features of human ubiquitin-like SUMO genes and their encoded proteins. |
Volume: |
296 |
Issue: |
1-2 |
Pages: |
65-73 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
628
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
430
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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•
•
•
•
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