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Search results 401 to 500 out of 2570 for Kras

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Category: Publication
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Type Details Score
Publication
22509024 | J:183916
First Author: Kang R
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia.
Volume: 109
Issue: 18
Pages: 7031-6
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Publication
34156985 | J:310404
 
First Author: Homayun-Sepehr N
Year: 2021
Journal: JCI Insight
Title: KRAS-driven model of Gorham-Stout disease effectively treated with trametinib.
Volume: 6
Issue: 15
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Publication
26516699 | J:316707
First Author: Rachagani S
Year: 2015
Journal: Oncotarget
Title: Changes in microRNA (miRNA) expression during pancreatic cancer development and progression in a genetically engineered KrasG12D;Pdx1-Cre mouse (KC) model.
Volume: 6
Issue: 37
Pages: 40295-309
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Publication
36635501 | J:348732
First Author: Tang R
Year: 2023
Journal: Nat Cell Biol
Title: Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth.
Volume: 25
Issue: 1
Pages: 159-169
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Publication
23578383 | J:198521
First Author: Al Saati T
Year: 2013
Journal: Am J Pathol
Title: Oxidative stress induced by inactivation of TP53INP1 cooperates with KrasG12D to initiate and promote pancreatic carcinogenesis in the murine pancreas.
Volume: 182
Issue: 6
Pages: 1996-2004
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Publication
32709695 | J:348810
 
First Author: Mallya K
Year: 2020
Journal: Biol Open
Title: Acinar transformed ductal cells exhibit differential mucin expression in a tamoxifen-induced pancreatic ductal adenocarcinoma mouse model.
Volume: 9
Issue: 9
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Publication
32029896 | J:291130
First Author: Li JT
Year: 2020
Journal: Nat Cell Biol
Title: BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma.
Volume: 22
Issue: 2
Pages: 167-174
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Publication
30008881 | J:299376
First Author: Noguchi K
Year: 2018
Journal: Oncol Lett
Title: c-Met affects gemcitabine resistance during carcinogenesis in a mouse model of pancreatic cancer.
Volume: 16
Issue: 2
Pages: 1892-1898
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Publication
32541781 | J:296715
First Author: Hidalgo-Sastre A
Year: 2020
Journal: Sci Rep
Title: Mir34a constrains pancreatic carcinogenesis.
Volume: 10
Issue: 1
Pages: 9654
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Publication
31534627 | J:298180
First Author: Ueda Y
Year: 2019
Journal: Oncotarget
Title: Application of C. elegans cancer screening test for the detection of pancreatic tumor in genetically engineered mice.
Volume: 10
Issue: 52
Pages: 5412-5418
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Publication
38654064 | J:348256
First Author: Wiley MB
Year: 2024
Journal: Sci Rep
Title: Activin A signaling stimulates neutrophil activation and macrophage migration in pancreatitis.
Volume: 14
Issue: 1
Pages: 9382
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Publication
38834136 | J:349887
 
First Author: Rogers JH
Year: 2024
Journal: Exp Hematol
Title: Dose-dependent effects of Dnmt3a in an inducible murine model of Kras(G12D)-driven leukemia.
Volume: 135
Pages: 104248
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Publication
21311774 | J:170906
First Author: Ray KC
Year: 2011
Journal: PLoS One
Title: Epithelial tissues have varying degrees of susceptibility to Kras(G12D)-initiated tumorigenesis in a mouse model.
Volume: 6
Issue: 2
Pages: e16786
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Publication
33891893 | J:328621
First Author: Hill W
Year: 2021
Journal: Curr Biol
Title: EPHA2-dependent outcompetition of KRASG12D mutant cells by wild-type neighbors in the adult pancreas.
Volume: 31
Issue: 12
Pages: 2550-2560.e5
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Publication
21984419 | J:183335
First Author: Aichler M
Year: 2012
Journal: J Pathol
Title: Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues.
Volume: 226
Issue: 5
Pages: 723-34
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Publication
31000598 | J:275811
First Author: Lim JKM
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance.
Volume: 116
Issue: 19
Pages: 9433-9442
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Publication
25341034 | J:318256
 
First Author: Kang R
Year: 2014
Journal: Cell Death Dis
Title: RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer.
Volume: 5
Pages: e1480
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Publication
36538983 | J:332974
 
First Author: Yang J
Year: 2023
Journal: Cancer Lett
Title: Miz1 promotes KRAS-driven lung tumorigenesis by repressing the protocadherin Pcdh10.
Volume: 555
Pages: 216025
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Publication
37730692 | J:340789
First Author: Baltanás FC
Year: 2023
Journal: Nat Commun
Title: Critical requirement of SOS1 for tumor development and microenvironment modulation in KRAS(G12D)-driven lung adenocarcinoma.
Volume: 14
Issue: 1
Pages: 5856
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Publication
37643866 | J:340295
 
First Author: Spaan CN
Year: 2023
Journal: Life Sci Alliance
Title: Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis.
Volume: 6
Issue: 11
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Publication
39213022 | J:361505
   
First Author: Ghazi PC
Year: 2024
Journal: Elife
Title: Inhibition of ULK1/2 and KRAS(G12C) controls tumor growth in preclinical models of lung cancer.
Volume: 13
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Publication
22022614 | J:179772
First Author: Regala RP
Year: 2011
Journal: PLoS One
Title: Matrix metalloproteinase-10 promotes Kras-mediated bronchio-alveolar stem cell expansion and lung cancer formation.
Volume: 6
Issue: 10
Pages: e26439
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Publication
38272100 | J:346390
     
First Author: Won Y
Year: 2024
Journal: Gastroenterology
Title: Oncogenic Fatty Acid Metabolism Rewires Energy Supply Chain in Gastric Carcinogenesis.
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Publication
21512139 | J:172206
First Author: Young NP
Year: 2011
Journal: Cancer Res
Title: Uncoupling cancer mutations reveals critical timing of p53 loss in sarcomagenesis.
Volume: 71
Issue: 11
Pages: 4040-7
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Publication
22897852 | J:191822
First Author: Maraver A
Year: 2012
Journal: Cancer Cell
Title: Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK.
Volume: 22
Issue: 2
Pages: 222-34
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Publication
26973251 | J:235984
First Author: Bigi A
Year: 2016
Journal: Oncogene
Title: Cyclophilin D counteracts P53-mediated growth arrest and promotes Ras tumorigenesis.
Volume: 35
Issue: 39
Pages: 5132-43
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Publication
24264992 | J:205193
First Author: Vermeulen L
Year: 2013
Journal: Science
Title: Defining stem cell dynamics in models of intestinal tumor initiation.
Volume: 342
Issue: 6161
Pages: 995-8
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Publication
34079126 | J:322623
First Author: Yum MK
Year: 2021
Journal: Nature
Title: Tracing oncogene-driven remodelling of the intestinal stem cell niche.
Volume: 594
Issue: 7863
Pages: 442-447
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Publication
36351408 | J:331107
First Author: Ramakrishnan G
Year: 2022
Journal: Cell Rep
Title: NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.
Volume: 41
Issue: 6
Pages: 111623
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Publication
30013058 | J:266243
First Author: Grzeskowiak CL
Year: 2018
Journal: Nat Commun
Title: In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer.
Volume: 9
Issue: 1
Pages: 2732
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Publication
29334357 | J:256834
   
First Author: Chua CW
Year: 2018
Journal: Elife
Title: Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation.
Volume: 7
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Publication
24097820 | J:205411
First Author: Zhang Y
Year: 2013
Journal: Cancer Res
Title: Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance.
Volume: 73
Issue: 20
Pages: 6359-74
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Publication
17676052 | J:125101
First Author: Kirsch DG
Year: 2007
Journal: Nat Med
Title: A spatially and temporally restricted mouse model of soft tissue sarcoma.
Volume: 13
Issue: 8
Pages: 992-7
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Publication
33414552 | J:302321
First Author: Najumudeen AK
Year: 2021
Journal: Nat Genet
Title: The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer.
Volume: 53
Issue: 1
Pages: 16-26
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Publication
36516772 | J:332395
First Author: Sessions DT
Year: 2022
Journal: Cell Rep
Title: Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD(+) regeneration in KRas-mutant lung adenocarcinoma.
Volume: 41
Issue: 11
Pages: 111818
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Publication
24561622 | J:212984
First Author: von Figura G
Year: 2014
Journal: Nat Cell Biol
Title: The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma.
Volume: 16
Issue: 3
Pages: 255-67
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Publication
26091037 | J:223512
First Author: Dow LE
Year: 2015
Journal: Cell
Title: Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer.
Volume: 161
Issue: 7
Pages: 1539-1552
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Publication
31266893 | J:278206
First Author: Torres C
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: p110γ deficiency protects against pancreatic carcinogenesis yet predisposes to diet-induced hepatotoxicity.
Volume: 116
Issue: 29
Pages: 14724-14733
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Publication
30938713 | J:308939
   
First Author: Cruz VH
Year: 2019
Journal: JCI Insight
Title: Axl-mediated activation of TBK1 drives epithelial plasticity in pancreatic cancer.
Volume: 5
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Publication
31801083 | J:296787
First Author: Li H
Year: 2019
Journal: Cell Rep
Title: YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression.
Volume: 29
Issue: 10
Pages: 3200-3211.e4
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Publication
37774698 | J:341369
First Author: Zhu M
Year: 2023
Journal: Cancer Cell
Title: Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden.
Volume: 41
Issue: 10
Pages: 1731-1748.e8
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Publication
27174785 | J:241552
First Author: Hernández-Porras I
Year: 2016
Journal: J Pathol
Title: K-Ras(V14I) -induced Noonan syndrome predisposes to tumour development in mice.
Volume: 239
Issue: 2
Pages: 206-17
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Publication
35120601 | J:320538
First Author: Alam A
Year: 2022
Journal: Cancer Cell
Title: Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer.
Volume: 40
Issue: 2
Pages: 153-167.e11
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Publication
36477656 | J:332124
First Author: Flanagan DJ
Year: 2022
Journal: Nat Commun
Title: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.
Volume: 13
Issue: 1
Pages: 7551
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Publication
26585400 | J:227252
First Author: Hayakawa Y
Year: 2015
Journal: Cancer Cell
Title: Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche.
Volume: 28
Issue: 6
Pages: 800-814
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Publication
21536023 | J:173640
First Author: Qu X
Year: 2011
Journal: Dev Biol
Title: Genetic epistasis between heparan sulfate and FGF-Ras signaling controls lens development.
Volume: 355
Issue: 1
Pages: 12-20
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Publication
36001969 | J:328042
First Author: Wang T
Year: 2022
Journal: Cell Rep
Title: The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations.
Volume: 40
Issue: 8
Pages: 111210
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Publication
21996748 | J:186130
First Author: Whipple CA
Year: 2012
Journal: Oncogene
Title: A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis.
Volume: 31
Issue: 20
Pages: 2535-44
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Publication
31740923 | J:296248
First Author: Giopanou I
Year: 2020
Journal: Carcinogenesis
Title: Osteopontin drives KRAS-mutant lung adenocarcinoma.
Volume: 41
Issue: 8
Pages: 1134-1144
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Publication
20080688 | J:156532
First Author: Hung KE
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.
Volume: 107
Issue: 4
Pages: 1565-70
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Publication
22266220 | J:184949
First Author: O'Dell MR
Year: 2012
Journal: Cancer Res
Title: Kras(G12D) and p53 mutation cause primary intrahepatic cholangiocarcinoma.
Volume: 72
Issue: 6
Pages: 1557-67
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Publication
20807812 | J:164210
First Author: Hill R
Year: 2010
Journal: Cancer Res
Title: PTEN loss accelerates KrasG12D-induced pancreatic cancer development.
Volume: 70
Issue: 18
Pages: 7114-24
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Publication
19847165 | J:154041
First Author: Meylan E
Year: 2009
Journal: Nature
Title: Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma.
Volume: 462
Issue: 7269
Pages: 104-7
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23285300 | J:195738
First Author: Lin C
Year: 2012
Journal: PLoS One
Title: Alveolar type II cells possess the capability of initiating lung tumor development.
Volume: 7
Issue: 12
Pages: e53817
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Publication
21408169 | J:171709
First Author: Miller SJ
Year: 2011
Journal: PLoS One
Title: In vivo fluorescence-based endoscopic detection of colon dysplasia in the mouse using a novel peptide probe.
Volume: 6
Issue: 3
Pages: e17384
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Publication
30655555 | J:275289
First Author: Menon M
Year: 2019
Journal: Sci Rep
Title: A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors.
Volume: 9
Issue: 1
Pages: 201
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Publication
31484658 | J:295220
First Author: Del Prete A
Year: 2019
Journal: Cancer Immunol Res
Title: The Atypical Receptor CCRL2 Is Essential for Lung Cancer Immune Surveillance.
Volume: 7
Issue: 11
Pages: 1775-1788
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Publication
31036704 | J:285455
 
First Author: Wang X
Year: 2019
Journal: EMBO Mol Med
Title: Nf1 loss promotes Kras-driven lung adenocarcinoma and results in Psat1-mediated glutamate dependence.
Volume: 11
Issue: 6
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18509000 | J:149009
First Author: Hammoud Z
Year: 2008
Journal: Endocr Relat Cancer
Title: Estrogen promotes tumor progression in a genetically defined mouse model of lung adenocarcinoma.
Volume: 15
Issue: 2
Pages: 475-83
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24307564 | J:208063
First Author: Rodriguez E
Year: 2014
Journal: J Pathol
Title: Versatile and enhanced tumour modelling in mice via somatic cell transduction.
Volume: 232
Issue: 4
Pages: 449-57
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28967920 | J:251982
First Author: Romero R
Year: 2017
Journal: Nat Med
Title: Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.
Volume: 23
Issue: 11
Pages: 1362-1368
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27702896 | J:238629
First Author: McFadden DG
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma.
Volume: 113
Issue: 42
Pages: E6409-E6417
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20595231 | J:161357
First Author: Zhao Z
Year: 2010
Journal: Genes Dev
Title: p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal.
Volume: 24
Issue: 13
Pages: 1389-402
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30753336 | J:288706
     
First Author: Ochiai M
Year: 2019
Journal: Carcinogenesis
Title: Kras-driven heterotopic tumor development from hepatobiliary organoids.
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30626590 | J:273222
First Author: Carrer A
Year: 2019
Journal: Cancer Discov
Title: Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis.
Volume: 9
Issue: 3
Pages: 416-435
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33998997 | J:308273
   
First Author: Li S
Year: 2021
Journal: Elife
Title: Signaling levels mold the RAS mutation tropism of urethane.
Volume: 10
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27338794 | J:235729
First Author: Manchado E
Year: 2016
Journal: Nature
Title: A combinatorial strategy for treating KRAS-mutant lung cancer.
Volume: 534
Issue: 7609
Pages: 647-51
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30956771 | J:298276
First Author: Khatri A
Year: 2019
Journal: Oncotarget
Title: ABL kinase inhibition sensitizes primary lung adenocarcinomas to chemotherapy by promoting tumor cell differentiation.
Volume: 10
Issue: 20
Pages: 1874-1886
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Publication
23891977 | J:310917
First Author: Greer RL
Year: 2013
Journal: Gastroenterology
Title: Numb regulates acinar cell dedifferentiation and survival during pancreatic damage and acinar-to-ductal metaplasia.
Volume: 145
Issue: 5
Pages: 1088-1097.e8
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37310065 | J:359038
First Author: Namikawa M
Year: 2023
Journal: J Pathol
Title: Simultaneous activation of Kras-Akt and Notch pathways induces extrahepatic biliary cancer via the mTORC1 pathway.
Volume: 260
Issue: 4
Pages: 478-492
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32221533 | J:299115
First Author: Böttinger P
Year: 2020
Journal: Carcinogenesis
Title: Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens.
Volume: 41
Issue: 11
Pages: 1605-1615
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23744837 | J:199569
First Author: Janzen DM
Year: 2013
Journal: Cancer Res
Title: Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy.
Volume: 73
Issue: 15
Pages: 4697-710
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25801914 | J:224952
First Author: Chang YI
Year: 2015
Journal: Leukemia
Title: Loss of Dnmt3a and endogenous Kras(G12D/+) cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis.
Volume: 29
Issue: 9
Pages: 1847-56
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24569456 | J:209632
First Author: Gritsman K
Year: 2014
Journal: J Clin Invest
Title: Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110α.
Volume: 124
Issue: 4
Pages: 1794-809
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18356293 | J:133578
First Author: Podsypanina K
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras.
Volume: 105
Issue: 13
Pages: 5242-7
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24114272 | J:201963
First Author: Song Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Evolutionary etiology of high-grade astrocytomas.
Volume: 110
Issue: 44
Pages: 17933-8
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34249932 | J:308024
 
First Author: Urrutia G
Year: 2021
Journal: Front Cell Dev Biol
Title: Inactivation of the Euchromatic Histone-Lysine N-Methyltransferase 2 Pathway in Pancreatic Epithelial Cells Antagonizes Cancer Initiation and Pancreatitis-Associated Promotion by Altering Growth and Immune Gene Expression Networks.
Volume: 9
Pages: 681153
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35815941 | J:326849
   
First Author: Kerk SA
Year: 2022
Journal: Elife
Title: Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context.
Volume: 11
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Publication
33864001 | J:305481
First Author: Azizi N
Year: 2021
Journal: Oncogene
Title: Loss of activating transcription factor 3 prevents KRAS-mediated pancreatic cancer.
Volume: 40
Issue: 17
Pages: 3118-3135
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Publication
25628462 | J:260326
First Author: Bowman BM
Year: 2015
Journal: Sci Signal
Title: Phosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer.
Volume: 8
Issue: 361
Pages: ra9
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Publication
26404002 | J:226774
First Author: Loncle C
Year: 2015
Journal: Cancer Res
Title: IL17 Functions through the Novel REG3β-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer.
Volume: 75
Issue: 22
Pages: 4852-62
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25042889 | J:214846
First Author: Yamaguchi T
Year: 2014
Journal: J Pathol
Title: A genetically engineered mouse model developing rapid progressive pancreatic ductal adenocarcinoma.
Volume: 234
Issue: 2
Pages: 228-38
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Publication
32580961 | J:296304
First Author: Wang F
Year: 2020
Journal: Cancer Res
Title: p38γ MAPK Is Essential for Aerobic Glycolysis and Pancreatic Tumorigenesis.
Volume: 80
Issue: 16
Pages: 3251-3264
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Publication
21896780 | J:178325
First Author: Ahn YH
Year: 2011
Journal: Mol Cell Biol
Title: Map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor γ2 expression.
Volume: 31
Issue: 21
Pages: 4270-85
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Publication
24632531 | J:210824
First Author: Byun AJ
Year: 2014
Journal: Cancer Lett
Title: Colon-specific tumorigenesis in mice driven by Cre-mediated inactivation of Apc and activation of mutant Kras.
Volume: 347
Issue: 2
Pages: 191-5
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Publication
31527715 | J:306834
First Author: Parameswaran N
Year: 2019
Journal: Sci Rep
Title: A FAM83A Positive Feed-back Loop Drives Survival and Tumorigenicity of Pancreatic Ductal Adenocarcinomas.
Volume: 9
Issue: 1
Pages: 13396
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Publication
28539837 | J:265014
First Author: Wang Y
Year: 2017
Journal: Int J Biol Sci
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