Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
Not Specified |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Glial fibrillary acidic protein (GFAP), a class-III intermediate filament, is a cell-specific marker that distinguishes astrocytes from other glial cells during the development of the central nervous system [, ]. Defects in GFAP are a cause of Alexander disease (ALEXD), which is a rare disorder of the central nervous system []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6479756 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-12-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1716828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6479827 |
Age: |
postnatal adult |
Image: |
2d GFAP OG/OG |
Note: |
Authors report absence of marked GFAP induction indicating healthy photoreceptors. |
Specimen Label: |
2d GFAP OG/OG |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7611615 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-03-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1903728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7611625 |
Age: |
postnatal adult |
Image: |
S6D GFAP |
|
Specimen Label: |
S6D GFAP |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7611615 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-03-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7611625 |
Age: |
postnatal adult |
Image: |
S3A GFAP |
|
Specimen Label: |
S3A GFAP |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7611615 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2024-03-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1903728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7611625 |
Age: |
postnatal adult |
Image: |
S3B GFAP |
|
Specimen Label: |
S3B GFAP |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nielsen AL |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
A new splice variant of glial fibrillary acidic protein, GFAP epsilon, interacts with the presenilin proteins. |
Volume: |
277 |
Issue: |
33 |
Pages: |
29983-91 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
430
|
Fragment?: |
false |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5447937 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2007-07-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778728 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3716146 |
Age: |
postnatal day 7 |
Image: |
6C +/+ GFAP |
|
Specimen Label: |
6C +/+ GFAP |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5447937 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2007-07-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778728 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3716146 |
Age: |
postnatal day 7 |
Image: |
6C nur12 GFAP |
Note: |
Expressing cells are poorly organized. |
Specimen Label: |
6C nur12 GFAP |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5300778 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2012-01-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284728 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:5301170 |
Age: |
postnatal day 4 |
Image: |
6C GFAP right |
Note: |
Sparse positive satellite glia, with fewer processes compared with controls. |
Specimen Label: |
6C GFAP right |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5300778 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2012-01-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1715728 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:5301170 |
Age: |
postnatal day 4 |
Image: |
6D GFAP left |
Note: |
Expressed in satellite glia. |
Specimen Label: |
6D GFAP left |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5300778 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2012-01-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1715728 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:5301170 |
Age: |
postnatal day 4 |
Image: |
6D GFAP right |
Note: |
Sparse positive satellite glia, with fewer processes compared with controls. |
Specimen Label: |
6D GFAP right |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5300778 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2012-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:5301122 |
Age: |
postnatal day 4 |
Image: |
S4 GFAP mut |
Note: |
Sparse positive satellite glia, with fewer processes compared with controls. Unlike in control, no honeycomb-like pattern was evident. |
Specimen Label: |
S4 GFAP mut |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7432916 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:7432930 |
Age: |
embryonic day 18.5 |
Image: |
S12 NesCreT/+ GFAP (lower) |
|
Specimen Label: |
S12 NesCreT/+ GFAP (lower) |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6436319 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-11-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691028 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7547347 |
Age: |
postnatal adult |
Image: |
5E GFAP Cenpj+/+ (right) |
Note: |
Expressing cells highly enriched on surface of lateral ventricle. |
Specimen Label: |
5E GFAP Cenpj+/+ (right) |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6436319 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-11-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3267928 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7547347 |
Age: |
postnatal day 40 |
Image: |
5H GFAP Cenpj+/+CiliaGFP/+ |
Note: |
Expression in B1 neural stem cells. |
Specimen Label: |
5H GFAP Cenpj+/+CiliaGFP/+ |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6436319 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-11-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3267928 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7547347 |
Age: |
postnatal day 40 |
Image: |
5I GFAP Cenpj+/+CiliaGFP/+ |
Note: |
Expression in B1 neural stem cells. |
Specimen Label: |
5I GFAP Cenpj+/+CiliaGFP/+ |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5300778 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2012-01-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:5301170 |
Age: |
postnatal day 4 |
Image: |
6C GFAP left |
Note: |
Expressed in satellite glia. |
Specimen Label: |
6C GFAP left |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5300778 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2012-01-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:5301122 |
Age: |
postnatal day 4 |
Image: |
S4 GFAP wt |
Note: |
Expressed in satellite glia. Present in a honeycomb-like pattern. |
Specimen Label: |
S4 GFAP wt |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6384823 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-01-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3522328 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:6384845 |
Age: |
postnatal day 21 |
Image: |
10B Elmo2 + GFAP |
Note: |
Expression in Bergmann glia with cell bodies localized in Purkinje cell layer. |
Specimen Label: |
10B Elmo2 + GFAP |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6479756 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-12-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1716828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6479827 |
Age: |
postnatal adult |
Image: |
2d GFAP +/OG |
|
Specimen Label: |
2d GFAP +/OG |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7432916 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:7432930 |
Age: |
embryonic day 18.5 |
Image: |
S12 NesCreT/+ GFAP (upper) |
|
Specimen Label: |
S12 NesCreT/+ GFAP (upper) |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7432916 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:7432930 |
Age: |
embryonic day 18.5 |
Image: |
S12 NesCreT/+ GFAP (middle) |
|
Specimen Label: |
S12 NesCreT/+ GFAP (middle) |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6436319 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1716828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7461929 |
Age: |
postnatal day 7 |
Image: |
11a GFAP C3H |
|
Specimen Label: |
11a GFAP C3H |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6436319 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619828 |
Pattern: |
Widespread |
Stage: |
TS28 |
Assay Id: |
MGI:7461929 |
Age: |
postnatal day 7 |
Image: |
11a GFAP Aey69 |
Note: |
Expression covering entire 'empty lens area' of mutant eye. |
Specimen Label: |
11a GFAP Aey69 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7509958 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-07-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3277028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7510016 |
Age: |
postnatal week 4 |
Image: |
3A GFAP +/+ |
|
Specimen Label: |
3A GFAP +/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7509958 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-07-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3277028 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7510016 |
Age: |
postnatal week 4 |
Image: |
3A GFAP tn/tn |
Note: |
No increase in expression compared to wild type. |
Specimen Label: |
3A GFAP tn/tn |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6436319 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-11-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691028 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7547347 |
Age: |
postnatal adult |
Image: |
5E GFAP Cenpj+/+ (left) |
Note: |
Expressing cells highly enriched on surface of lateral ventricle. |
Specimen Label: |
5E GFAP Cenpj+/+ (left) |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6436319 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-11-10 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691028 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7547347 |
Age: |
postnatal adult |
Image: |
5E GFAP CenpjCKO (left) |
Note: |
Only a few expressing cells were observed. |
Specimen Label: |
5E GFAP CenpjCKO (left) |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6436319 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-11-10 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691028 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7547347 |
Age: |
postnatal adult |
Image: |
5E GFAP CenpjCKO (right) |
Note: |
Only a few expressing cells were observed |
Specimen Label: |
5E GFAP CenpjCKO (right) |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6436319 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-11-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3280428 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7547347 |
Age: |
postnatal day 40 |
Image: |
5H GFAP Cenpj+/+CiliaGFP/+ |
Note: |
Expression in B1 neural stem cells. |
Specimen Label: |
5H GFAP Cenpj+/+CiliaGFP/+ |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6436319 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-11-10 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:3280428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7547347 |
Age: |
postnatal day 40 |
Image: |
5H GFAP CenpjCKOCiliaGFP/+ |
Note: |
Expression reduced compared to wild type. |
Specimen Label: |
5H GFAP CenpjCKOCiliaGFP/+ |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6436319 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-11-10 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:3267928 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7547347 |
Age: |
postnatal day 40 |
Image: |
5H GFAP CenpjCKOCiliaGFP/+ |
Note: |
Expression reduced compared to wild type. |
Specimen Label: |
5H GFAP CenpjCKOCiliaGFP/+ |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6436319 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-11-10 |
Strength: |
Trace |
Sex: |
Not Specified |
Emaps: |
EMAPS:3280428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7547347 |
Age: |
postnatal day 40 |
Image: |
5I GFAP CenpjCKOCiliaGFP/+ |
Note: |
Expression reduced compared to wild type. |
Specimen Label: |
5I GFAP CenpjCKOCiliaGFP/+ |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bongcam-Rudloff E |
Year: |
1991 |
Journal: |
Cancer Res |
Title: |
Human glial fibrillary acidic protein: complementary DNA cloning, chromosome localization, and messenger RNA expression in human glioma cell lines of various phenotypes. |
Volume: |
51 |
Issue: |
5 |
Pages: |
1553-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stumpf E |
Year: |
2003 |
Journal: |
Arch Neurol |
Title: |
Adult Alexander disease with autosomal dominant transmission: a distinct entity caused by mutation in the glial fibrillary acid protein gene. |
Volume: |
60 |
Issue: |
9 |
Pages: |
1307-12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5588106 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2014-10-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1903728 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:5588104 |
Age: |
postnatal adult |
Image: |
4 hippocampus CDCrel-1 + Gfap |
Note: |
Expression in glia. |
Specimen Label: |
4 hippocampus CDCrel-1 + Gfap |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5906476 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2017-08-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3276828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5906617 |
Age: |
postnatal month 8 |
Image: |
5A GFAP WT 8 months |
|
Specimen Label: |
5A GFAP WT 8 months |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5906476 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2017-08-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3276828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5906617 |
Age: |
postnatal month 8 |
Image: |
5A GFAP Miro1cko 8 months |
|
Specimen Label: |
5A GFAP Miro1cko 8 months |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5906476 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2017-08-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3276828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5906617 |
Age: |
postnatal month 12 |
Image: |
5C GFAP WT 12 months |
|
Specimen Label: |
5C GFAP WT 12 months |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5906476 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2017-08-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3276828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5906617 |
Age: |
postnatal month 12 |
Image: |
5C GFAP Miro1cko 12 months |
|
Specimen Label: |
5C GFAP Miro1cko 12 months |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7432916 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754426 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:7432930 |
Age: |
embryonic day 18.5 |
Image: |
S12 Kat7lox/lox NesCreT/+ GFAP (upper) |
Note: |
Expressing cells in similar locations as in control, but less abundant. |
Specimen Label: |
S12 Kat7lox/lox NesCreT/+ GFAP (upper) |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7432916 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754426 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:7432930 |
Age: |
embryonic day 18.5 |
Image: |
S12 Kat7lox/lox NesCreT/+ GFAP (middle) |
|
Specimen Label: |
S12 Kat7lox/lox NesCreT/+ GFAP (middle) |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7432916 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754426 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:7432930 |
Age: |
embryonic day 18.5 |
Image: |
S12 Kat7lox/lox NesCreT/+ GFAP (lower) |
Note: |
Expressing cells in similar locations as in control, but less abundant. |
Specimen Label: |
S12 Kat7lox/lox NesCreT/+ GFAP (lower) |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
55
|
Fragment?: |
true |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7343764 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-10-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284222 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7343766 |
Age: |
embryonic day 14.5 |
Image: |
2 GFAP |
|
Specimen Label: |
2 GFAP |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7343764 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-10-05 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284222 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7343766 |
Age: |
embryonic day 14.5 |
Image: |
2 GFAP |
|
Specimen Label: |
2 GFAP |
Detected: |
false |
Specimen Num: |
8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cho W |
Year: |
2009 |
Journal: |
Exp Cell Res |
Title: |
Properties of astrocytes cultured from GFAP over-expressing and GFAP mutant mice. |
Volume: |
315 |
Issue: |
7 |
Pages: |
1260-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nawashiro H |
Year: |
1998 |
Journal: |
Neuroreport |
Title: |
Mice lacking GFAP are hypersensitive to traumatic cerebrospinal injury. |
Volume: |
9 |
Issue: |
8 |
Pages: |
1691-6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7398565 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-12-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7398600 |
Age: |
postnatal adult |
|
|
Specimen Label: |
3D GFAP |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7495927 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-07-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689427 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7495940 |
Age: |
postnatal newborn |
|
|
Specimen Label: |
S1 GFAP |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7495927 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-07-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7495940 |
Age: |
postnatal adult |
|
|
Specimen Label: |
3 GFAP |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7398565 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-12-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7398600 |
Age: |
postnatal adult |
|
|
Specimen Label: |
3E GFAP |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yuan W |
Year: |
2021 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
GFAP hyperpalmitoylation exacerbates astrogliosis and neurodegenerative pathology in PPT1-deficient mice. |
Volume: |
118 |
Issue: |
13 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Tang G |
Year: |
2008 |
Journal: |
Hum Mol Genet |
Title: |
Autophagy induced by Alexander disease-mutant GFAP accumulation is regulated by p38/MAPK and mTOR signaling pathways. |
Volume: |
17 |
Issue: |
11 |
Pages: |
1540-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jurado-Arjona J |
Year: |
2019 |
Journal: |
Brain Res |
Title: |
GSK3β overexpression driven by GFAP promoter improves rotarod performance. |
Volume: |
1712 |
|
Pages: |
47-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilhelmsson U |
Year: |
2019 |
Journal: |
Biol Chem |
Title: |
The role of GFAP and vimentin in learning and memory. |
Volume: |
400 |
Issue: |
9 |
Pages: |
1147-1156 |
|
•
•
•
•
•
|
Publication |
First Author: |
De Luca C |
Year: |
2022 |
Journal: |
Cells |
Title: |
Altered Spinal Homeostasis and Maladaptive Plasticity in GFAP Null Mice Following Peripheral Nerve Injury. |
Volume: |
11 |
Issue: |
7 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hagemann TL |
Year: |
2013 |
Journal: |
J Neurosci |
Title: |
Deficits in adult neurogenesis, contextual fear conditioning, and spatial learning in a Gfap mutant mouse model of Alexander disease. |
Volume: |
33 |
Issue: |
47 |
Pages: |
18698-706 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gomes FC |
Year: |
1999 |
Journal: |
Glia |
Title: |
Neurons induce GFAP gene promoter of cultured astrocytes from transgenic mice. |
Volume: |
26 |
Issue: |
2 |
Pages: |
97-108 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jany PL |
Year: |
2013 |
Journal: |
ASN Neuro |
Title: |
GFAP expression as an indicator of disease severity in mouse models of Alexander disease. |
Volume: |
5 |
Issue: |
1 |
Pages: |
e00109 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kothavale A |
Year: |
1995 |
Journal: |
Glia |
Title: |
GFAP mRNA fluctuates in synchrony with chronic relapsing EAE symptoms in SJL/J mice. |
Volume: |
14 |
Issue: |
3 |
Pages: |
216-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hanbury R |
Year: |
2003 |
Journal: |
J Comp Neurol |
Title: |
GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults. |
Volume: |
461 |
Issue: |
3 |
Pages: |
307-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanaka KF |
Year: |
2007 |
Journal: |
Glia |
Title: |
Murine model of Alexander disease: analysis of GFAP aggregate formation and its pathological significance. |
Volume: |
55 |
Issue: |
6 |
Pages: |
617-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hagemann TL |
Year: |
2009 |
Journal: |
Hum Mol Genet |
Title: |
Suppression of GFAP toxicity by alphaB-crystallin in mouse models of Alexander disease. |
Volume: |
18 |
Issue: |
7 |
Pages: |
1190-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Galou M |
Year: |
1994 |
Journal: |
Glia |
Title: |
Normal and pathological expression of GFAP promoter elements in transgenic mice. |
Volume: |
12 |
Issue: |
4 |
Pages: |
281-93 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7495927 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-07-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7495940 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2 GFAP Cortex |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7495927 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-07-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7495940 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2 GFAP Hippocampus |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7495927 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-07-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7495940 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2 GFAP Cerebellum |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7495927 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-07-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7495940 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2 GFAP Lateral ventricle |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7495927 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-07-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1697428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7495940 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2 GFAP Midbrain |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7495927 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-07-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7495940 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2 GFAP Corpus callosum |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7528962 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-09-20 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3276828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7528982 |
Age: |
postnatal adult |
|
|
Specimen Label: |
5A GFAP wt |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7528962 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-09-20 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3276828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7528982 |
Age: |
postnatal adult |
|
Note: |
Authors report massive astrogiosis in CA3 region. |
Specimen Label: |
5A GFAP ko |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Keller AF |
Year: |
2009 |
Journal: |
Glia |
Title: |
Live imaging of amyotrophic lateral sclerosis pathogenesis: disease onset is characterized by marked induction of GFAP in Schwann cells. |
Volume: |
57 |
Issue: |
10 |
Pages: |
1130-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hagemann TL |
Year: |
2023 |
Journal: |
Cells |
Title: |
STAT3 Drives GFAP Accumulation and Astrocyte Pathology in a Mouse Model of Alexander Disease. |
Volume: |
12 |
Issue: |
7 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shibuki K |
Year: |
1996 |
Journal: |
Neuron |
Title: |
Deficient cerebellar long-term depression, impaired eyeblink conditioning, and normal motor coordination in GFAP mutant mice. |
Volume: |
16 |
Issue: |
3 |
Pages: |
587-99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liedtke W |
Year: |
1996 |
Journal: |
Neuron |
Title: |
GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination. |
Volume: |
17 |
Issue: |
4 |
Pages: |
607-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanaka H |
Year: |
2002 |
Journal: |
J Neurosci Res |
Title: |
Disturbance of hippocampal long-term potentiation after transient ischemia in GFAP deficient mice. |
Volume: |
67 |
Issue: |
1 |
Pages: |
11-20 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6384816 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-01-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3522328 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:6384838 |
Age: |
postnatal day 21 |
Image: |
10B Elmo2 + GFAP |
Note: |
Exprssion in Gfap-expressing Bergmann glial cells with cell bodies in the Purkinje cell layer. |
Specimen Label: |
10B Elmo2 + GFAP |
Detected: |
true |
Specimen Num: |
39 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6887449 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-03-09 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6887612 |
Age: |
postnatal |
Image: |
1D WT GFAP |
|
Specimen Label: |
1D WT GFAP |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilhelmsson U |
Year: |
2003 |
Journal: |
Oncogene |
Title: |
Loss of GFAP expression in high-grade astrocytomas does not contribute to tumor development or progression. |
Volume: |
22 |
Issue: |
22 |
Pages: |
3407-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Minkel HR |
Year: |
2015 |
Journal: |
Glia |
Title: |
Elevated GFAP induces astrocyte dysfunction in caudal brain regions: A potential mechanism for hindbrain involved symptoms in type II Alexander disease. |
Volume: |
63 |
Issue: |
12 |
Pages: |
2285-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Verardo MR |
Year: |
2008 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Abnormal reactivity of muller cells after retinal detachment in mice deficient in GFAP and vimentin. |
Volume: |
49 |
Issue: |
8 |
Pages: |
3659-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mignot C |
Year: |
2007 |
Journal: |
Exp Cell Res |
Title: |
Dynamics of mutated GFAP aggregates revealed by real-time imaging of an astrocyte model of Alexander disease. |
Volume: |
313 |
Issue: |
13 |
Pages: |
2766-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cebolla B |
Year: |
2008 |
Journal: |
J Neurosci |
Title: |
DREAM mediates cAMP-dependent, Ca2+-induced stimulation of GFAP gene expression and regulates cortical astrogliogenesis. |
Volume: |
28 |
Issue: |
26 |
Pages: |
6703-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gomi H |
Year: |
2010 |
Journal: |
Brain Res |
Title: |
Role of GFAP in morphological retention and distribution of reactive astrocytes induced by scrapie encephalopathy in mice. |
Volume: |
1312 |
|
Pages: |
156-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Steward O |
Year: |
1997 |
Journal: |
Exp Neurol |
Title: |
Signals that regulate astroglial gene expression: induction of GFAP mRNA following seizures or injury is blocked by protein synthesis inhibitors. |
Volume: |
148 |
Issue: |
1 |
Pages: |
100-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Masuda M |
Year: |
2008 |
Journal: |
Neurosci Res |
Title: |
GFAP aggregates in the cochlear nerve increase the noise vulnerability of sensory cells in the organ of Corti in the murine model of Alexander disease. |
Volume: |
62 |
Issue: |
1 |
Pages: |
15-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Minn A |
Year: |
1998 |
Journal: |
Glia |
Title: |
Enhanced GFAP expression in astrocytes of transgenic mice expressing the human brain-specific trypsinogen IV. |
Volume: |
22 |
Issue: |
4 |
Pages: |
338-47 |
|
•
•
•
•
•
|