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Search results 1901 to 2000 out of 2080 for Lck

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Type Details Score
Publication
First Author: Bergsbaken T
Year: 2015
Journal: Nat Immunol
Title: Proinflammatory microenvironments within the intestine regulate the differentiation of tissue-resident CD8⁺ T cells responding to infection.
Volume: 16
Issue: 4
Pages: 406-14
Publication  
First Author: Smith CJ
Year: 2021
Journal: Front Immunol
Title: Inhibitory Molecules PD-1, CD73 and CD39 Are Expressed by CD8+ T Cells in a Tissue-Dependent Manner and Can Inhibit T Cell Responses to Stimulation.
Volume: 12
Pages: 704862
Publication
First Author: Tyrakis PA
Year: 2016
Journal: Nature
Title: S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate.
Volume: 540
Issue: 7632
Pages: 236-241
Publication
First Author: Mora AL
Year: 2001
Journal: J Immunol
Title: Inefficient ZAP-70 phosphorylation and decreased thymic selection in vivo result from inhibition of NF-kappaB/Rel.
Volume: 167
Issue: 10
Pages: 5628-35
Publication
First Author: Yao S
Year: 2013
Journal: Immunity
Title: Interferon regulatory factor 4 sustains CD8(+) T cell expansion and effector differentiation.
Volume: 39
Issue: 5
Pages: 833-45
Publication
First Author: Nolting J
Year: 2009
Journal: J Exp Med
Title: Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines.
Volume: 206
Issue: 10
Pages: 2131-9
Publication
First Author: Menzel U
Year: 2011
Journal: J Immunol
Title: Modulation of the murine CD8 gene complex following the targeted integration of human CD2-locus control region sequences.
Volume: 187
Issue: 7
Pages: 3712-20
Publication
First Author: Gao Y
Year: 1998
Journal: J Exp Med
Title: Antiinflammatory effects of CD95 ligand (FasL)-induced apoptosis.
Volume: 188
Issue: 5
Pages: 887-96
Publication
First Author: Molinero LL
Year: 2011
Journal: J Immunol
Title: High TCR stimuli prevent induced regulatory T cell differentiation in a NF-κB-dependent manner.
Volume: 186
Issue: 8
Pages: 4609-17
Publication
First Author: Jin J
Year: 2008
Journal: Science
Title: Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis.
Volume: 322
Issue: 5902
Pages: 756-60
Publication
First Author: Luche H
Year: 2007
Journal: Eur J Immunol
Title: Faithful activation of an extra-bright red fluorescent protein in "knock-in" Cre-reporter mice ideally suited for lineage tracing studies.
Volume: 37
Issue: 1
Pages: 43-53
Publication    
First Author: Umpierre AD
Year: 2020
Journal: Elife
Title: Microglial calcium signaling is attuned to neuronal activity in awake mice.
Volume: 9
Publication
First Author: Carofino BL
Year: 2013
Journal: Dis Model Mech
Title: A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Volume: 6
Issue: 6
Pages: 1494-506
Publication
First Author: Takahashi R
Year: 2017
Journal: J Immunol
Title: SOCS1 Is a Key Molecule That Prevents Regulatory T Cell Plasticity under Inflammatory Conditions.
Volume: 199
Issue: 1
Pages: 149-158
Publication
First Author: Vongpipatana T
Year: 2020
Journal: J Immunol
Title: ADAR1 Regulates Early T Cell Development via MDA5-Dependent and -Independent Pathways.
Volume: 204
Issue: 8
Pages: 2156-2168
Publication
First Author: Gerl M
Year: 2015
Journal: Kidney Int
Title: Inducible deletion of connexin 40 in adult mice causes hypertension and disrupts pressure control of renin secretion.
Volume: 87
Issue: 3
Pages: 557-63
Genotype
Symbol: Dhx9/Dhx9<+> Igs12/Igs12 Ptprc/Ptprc Tg(Lck-cre)#Zhu/?
Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/NJ * SJL/J
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Setoguchi R
Year: 2008
Journal: Science
Title: Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.
Volume: 319
Issue: 5864
Pages: 822-5
Publication
First Author: Mackay LK
Year: 2016
Journal: Science
Title: Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.
Volume: 352
Issue: 6284
Pages: 459-63
Publication
First Author: Gardam S
Year: 2008
Journal: Immunity
Title: TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor.
Volume: 28
Issue: 3
Pages: 391-401
Publication
First Author: Aliahmad P
Year: 2008
Journal: J Exp Med
Title: Development of all CD4 T lineages requires nuclear factor TOX.
Volume: 205
Issue: 1
Pages: 245-56
Publication  
First Author: McKenzie DR
Year: 2017
Journal: Nat Commun
Title: IL-17-producing γδ T cells switch migratory patterns between resting and activated states.
Volume: 8
Pages: 15632
Publication
First Author: Park JH
Year: 2010
Journal: Nat Immunol
Title: Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells.
Volume: 11
Issue: 3
Pages: 257-64
Publication
First Author: Kovalovsky D
Year: 2009
Journal: J Immunol
Title: Beta-catenin/Tcf determines the outcome of thymic selection in response to alphabetaTCR signaling.
Volume: 183
Issue: 6
Pages: 3873-84
Publication
First Author: McCaughtry TM
Year: 2012
Journal: J Exp Med
Title: Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus.
Volume: 209
Issue: 12
Pages: 2263-76
Publication
First Author: Sasaki K
Year: 2019
Journal: Nat Commun
Title: Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death.
Volume: 10
Issue: 1
Pages: 3878
Publication  
First Author: Nowak N
Year: 2021
Journal: eNeuro
Title: Prior Acoustic Trauma Alters Type II Afferent Activity in the Mouse Cochlea.
Volume: 8
Issue: 6
Publication
First Author: Ahrends T
Year: 2021
Journal: Cell
Title: Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections.
Volume: 184
Issue: 23
Pages: 5715-5727.e12
Publication
First Author: Jabeen R
Year: 2013
Journal: J Clin Invest
Title: Th9 cell development requires a BATF-regulated transcriptional network.
Volume: 123
Issue: 11
Pages: 4641-53
Publication
First Author: Riesenberg BP
Year: 2022
Journal: Cancer Res
Title: Stress-Mediated Attenuation of Translation Undermines T-cell Activity in Cancer.
Volume: 82
Issue: 23
Pages: 4386-4399
Publication
First Author: Lee CL
Year: 2021
Journal: Cancer Res
Title: Whole-Exome Sequencing of Radiation-Induced Thymic Lymphoma in Mouse Models Identifies Notch1 Activation as a Driver of p53 Wild-Type Lymphoma.
Volume: 81
Issue: 14
Pages: 3777-3790
Publication
First Author: Timilshina M
Year: 2019
Journal: Cell Rep
Title: Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells.
Volume: 27
Issue: 10
Pages: 2948-2961.e7
Publication
First Author: Doedens AL
Year: 2013
Journal: Nat Immunol
Title: Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen.
Volume: 14
Issue: 11
Pages: 1173-82
Publication
First Author: Wang J
Year: 2017
Journal: Nat Commun
Title: NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoing positive selection.
Volume: 8
Issue: 1
Pages: 959
Publication
First Author: Ouyang X
Year: 2019
Journal: J Mol Cell Biol
Title: Metabolic regulation of T cell development by Sin1-mTORC2 is mediated by pyruvate kinase M2.
Volume: 11
Issue: 2
Pages: 93-106
Publication
First Author: Phelan JD
Year: 2013
Journal: PLoS Genet
Title: Growth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors.
Volume: 9
Issue: 9
Pages: e1003713
Publication
First Author: Poffenberger MC
Year: 2018
Journal: Science
Title: LKB1 deficiency in T cells promotes the development of gastrointestinal polyposis.
Volume: 361
Issue: 6400
Pages: 406-411
Publication
First Author: Vaeth M
Year: 2017
Journal: Immunity
Title: Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming.
Volume: 47
Issue: 4
Pages: 664-679.e6
Publication
First Author: Babbe H
Year: 2007
Journal: Mol Cell Biol
Title: The Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineage.
Volume: 27
Issue: 5
Pages: 1947-59
Publication
First Author: Philip M
Year: 2015
Journal: J Immunol
Title: Heme exporter FLVCR is required for T cell development and peripheral survival.
Volume: 194
Issue: 4
Pages: 1677-85
Publication
First Author: Cronin SJF
Year: 2018
Journal: Nature
Title: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.
Volume: 563
Issue: 7732
Pages: 564-568
Publication
First Author: Kojo S
Year: 2017
Journal: Nat Commun
Title: Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes.
Volume: 8
Issue: 1
Pages: 702
Publication
First Author: Kortum RL
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Targeted Sos1 deletion reveals its critical role in early T-cell development.
Volume: 108
Issue: 30
Pages: 12407-12
Publication
First Author: Seki Y
Year: 2007
Journal: J Immunol
Title: IL-7/STAT5 cytokine signaling pathway is essential but insufficient for maintenance of naive CD4 T cell survival in peripheral lymphoid organs.
Volume: 178
Issue: 1
Pages: 262-70
Publication
First Author: Fischer AM
Year: 2005
Journal: Immunity
Title: The role of erk1 and erk2 in multiple stages of T cell development.
Volume: 23
Issue: 4
Pages: 431-43
Publication
First Author: Mielke LA
Year: 2019
Journal: J Exp Med
Title: TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis.
Volume: 216
Issue: 7
Pages: 1682-1699
Publication
First Author: Zhang B
Year: 2014
Journal: J Immunol
Title: Id3 and Id2 act as a dual safety mechanism in regulating the development and population size of innate-like γδ T cells.
Volume: 192
Issue: 3
Pages: 1055-1063
Publication
First Author: Miyazaki M
Year: 2015
Journal: Genes Dev
Title: The E-Id protein axis modulates the activities of the PI3K-AKT-mTORC1-Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and lymphomagenesis.
Volume: 29
Issue: 4
Pages: 409-25
Publication
First Author: Pearce EL
Year: 2009
Journal: Nature
Title: Enhancing CD8 T-cell memory by modulating fatty acid metabolism.
Volume: 460
Issue: 7251
Pages: 103-7
Publication
First Author: Miwa T
Year: 2009
Journal: Blood
Title: Complement-dependent T-cell lymphopenia caused by thymocyte deletion of the membrane complement regulator Crry.
Volume: 113
Issue: 12
Pages: 2684-94
Publication
First Author: Kerdiles YM
Year: 2009
Journal: Nat Immunol
Title: Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.
Volume: 10
Issue: 2
Pages: 176-84
Publication
First Author: Beisner DR
Year: 2003
Journal: J Immunol
Title: The requirements for Fas-associated death domain signaling in mature T cell activation and survival.
Volume: 171
Issue: 1
Pages: 247-56
Publication
First Author: Pan L
Year: 2002
Journal: J Immunol
Title: An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus.
Volume: 168
Issue: 8
Pages: 3923-32
Publication
First Author: Okuma A
Year: 2013
Journal: Immunity
Title: Enhanced apoptosis by disruption of the STAT3-IκB-ζ signaling pathway in epithelial cells induces Sjögren's syndrome-like autoimmune disease.
Volume: 38
Issue: 3
Pages: 450-60
Publication  
First Author: Rudolph J
Year: 2019
Journal: Front Immunol
Title: Immune Cell-Type Specific Ablation of Adapter Protein ADAP Differentially Modulates EAE.
Volume: 10
Pages: 2343
Publication
First Author: Wang Z
Year: 2021
Journal: Autophagy
Title: Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation.
Volume: 17
Issue: 2
Pages: 529-552
Publication
First Author: Baschant U
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells.
Volume: 108
Issue: 48
Pages: 19317-22
Publication
First Author: Ritprajak P
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Cell type-specific targeting dissociates the therapeutic from the adverse effects of protein kinase inhibition in allergic skin disease.
Volume: 109
Issue: 23
Pages: 9089-94
Publication
First Author: Zheng M
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Protein phosphatase 2A has an essential role in promoting thymocyte survival during selection.
Volume: 116
Issue: 25
Pages: 12422-12427
Publication
First Author: Goh PK
Year: 2022
Journal: Sci Adv
Title: PTPN2 elicits cell autonomous and non-cell autonomous effects on antitumor immunity in triple-negative breast cancer.
Volume: 8
Issue: 8
Pages: eabk3338
Publication
First Author: Wiede F
Year: 2022
Journal: Cancer Discov
Title: PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity.
Volume: 12
Issue: 3
Pages: 752-773
Publication
First Author: Han D
Year: 2013
Journal: Immunity
Title: Dendritic cell expression of the signaling molecule TRAF6 is critical for gut microbiota-dependent immune tolerance.
Volume: 38
Issue: 6
Pages: 1211-22
Publication
First Author: Schmidt AM
Year: 2015
Journal: J Immunol
Title: Regulatory T cells require TCR signaling for their suppressive function.
Volume: 194
Issue: 9
Pages: 4362-70
Publication  
First Author: Chan CT
Year: 2020
Journal: J Exp Med
Title: Liver X receptors are required for thymic resilience and T cell output.
Volume: 217
Issue: 10
Publication
First Author: Peperzak V
Year: 2010
Journal: J Immunol
Title: The Pim kinase pathway contributes to survival signaling in primed CD8+ T cells upon CD27 costimulation.
Volume: 185
Issue: 11
Pages: 6670-8
Publication
First Author: Oh-Hora M
Year: 2013
Journal: Immunity
Title: Agonist-selected T cell development requires strong T cell receptor signaling and store-operated calcium entry.
Volume: 38
Issue: 5
Pages: 881-95
Publication
First Author: Keerthivasan S
Year: 2014
Journal: Sci Transl Med
Title: β-Catenin promotes colitis and colon cancer through imprinting of proinflammatory properties in T cells.
Volume: 6
Issue: 225
Pages: 225ra28
Publication
First Author: Gmyrek GB
Year: 2013
Journal: Eur J Immunol
Title: Polarity gene discs large homolog 1 regulates the generation of memory T cells.
Volume: 43
Issue: 5
Pages: 1185-94
Publication
First Author: Miller ML
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Basal NF-κB controls IL-7 responsiveness of quiescent naïve T cells.
Volume: 111
Issue: 20
Pages: 7397-402
Publication
First Author: Kotov JA
Year: 2019
Journal: J Exp Med
Title: BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors.
Volume: 216
Issue: 6
Pages: 1450-1464
Publication
First Author: Varanasi V
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Loss of the death receptor CD95 (Fas) expression by dendritic cells protects from a chronic viral infection.
Volume: 111
Issue: 23
Pages: 8559-64
Publication    
First Author: Philips RL
Year: 2019
Journal: Elife
Title: HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4+CD8+ thymocytes for CD4-lineage commitment.
Volume: 8
Publication
First Author: Kondo M
Year: 2016
Journal: J Immunol
Title: SATB1 Plays a Critical Role in Establishment of Immune Tolerance.
Volume: 196
Issue: 2
Pages: 563-72
Publication
First Author: Okamoto K
Year: 2010
Journal: Nature
Title: IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear receptors.
Volume: 464
Issue: 7293
Pages: 1381-5
Publication
First Author: Thom JT
Year: 2015
Journal: Cell Rep
Title: The Salivary Gland Acts as a Sink for Tissue-Resident Memory CD8(+) T Cells, Facilitating Protection from Local Cytomegalovirus Infection.
Volume: 13
Issue: 6
Pages: 1125-1136
Publication
First Author: Mendoza A
Year: 2017
Journal: Nature
Title: Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells.
Volume: 546
Issue: 7656
Pages: 158-161
Publication
First Author: Tripathi P
Year: 2013
Journal: Cell Death Differ
Title: Mcl-1 antagonizes Bax/Bak to promote effector CD4(+) and CD8(+) T-cell responses.
Volume: 20
Issue: 8
Pages: 998-1007
Publication  
First Author: Raynor J
Year: 2013
Journal: Front Immunol
Title: IL-15 Fosters Age-Driven Regulatory T Cell Accrual in the Face of Declining IL-2 Levels.
Volume: 4
Pages: 161
Publication
First Author: Yu HM
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Development of a unique system for spatiotemporal and lineage-specific gene expression in mice.
Volume: 102
Issue: 24
Pages: 8615-20
Publication
First Author: Gaddis DE
Year: 2019
Journal: J Immunol
Title: Neuropilin-1 Expression on CD4 T Cells Is Atherogenic and Facilitates T Cell Migration to the Aorta in Atherosclerosis.
Volume: 203
Issue: 12
Pages: 3237-3246
Publication
First Author: Van Welden S
Year: 2017
Journal: J Pathol
Title: Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.
Volume: 241
Issue: 4
Pages: 547-558
Publication  
First Author: Ligons DL
Year: 2018
Journal: Sci Signal
Title: RORγt limits the amount of the cytokine receptor γc through the prosurvival factor Bcl-xL in developing thymocytes.
Volume: 11
Issue: 545
Publication
First Author: Stranges PB
Year: 2007
Journal: Immunity
Title: Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity.
Volume: 26
Issue: 5
Pages: 629-41
Publication
First Author: Luche H
Year: 2013
Journal: J Exp Med
Title: In vivo fate mapping identifies pre-TCRα expression as an intra- and extrathymic, but not prethymic, marker of T lymphopoiesis.
Volume: 210
Issue: 4
Pages: 699-714
Publication
First Author: Khandanpour C
Year: 2013
Journal: Cancer Cell
Title: Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia.
Volume: 23
Issue: 2
Pages: 200-14
Publication
First Author: Mao C
Year: 2007
Journal: J Immunol
Title: Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition.
Volume: 178
Issue: 9
Pages: 5443-53
Publication
First Author: Haase VH
Year: 2005
Journal: Semin Cell Dev Biol
Title: The VHL tumor suppressor in development and disease: functional studies in mice by conditional gene targeting.
Volume: 16
Issue: 4-5
Pages: 564-74
Publication
First Author: Werlen G
Year: 2022
Journal: Nat Commun
Title: Dietary glucosamine overcomes the defects in αβ-T cell ontogeny caused by the loss of de novo hexosamine biosynthesis.
Volume: 13
Issue: 1
Pages: 7404
Publication
First Author: Zhao B
Year: 2019
Journal: Nat Immunol
Title: Notch and the pre-TCR coordinate thymocyte proliferation by induction of the SCF subunits Fbxl1 and Fbxl12.
Volume: 20
Issue: 10
Pages: 1381-1392
Publication
First Author: Williams CJ
Year: 2004
Journal: Immunity
Title: The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development.
Volume: 20
Issue: 6
Pages: 719-33
Publication
First Author: Hong SW
Year: 2022
Journal: Nature
Title: Immune tolerance of food is mediated by layers of CD4(+) T cell dysfunction.
Volume: 607
Issue: 7920
Pages: 762-768
Publication
First Author: Palazon A
Year: 2017
Journal: Cancer Cell
Title: An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression.
Volume: 32
Issue: 5
Pages: 669-683.e5
Publication
First Author: Jia W
Year: 2015
Journal: Autophagy
Title: Autophagy regulates T lymphocyte proliferation through selective degradation of the cell-cycle inhibitor CDKN1B/p27Kip1.
Volume: 11
Issue: 12
Pages: 2335-45
Publication
First Author: Zhu L
Year: 2018
Journal: Nat Commun
Title: TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival.
Volume: 9
Issue: 1
Pages: 2812
Publication
First Author: Kramer AC
Year: 2017
Journal: Leukemia
Title: Dnmt3a regulates T-cell development and suppresses T-ALL transformation.
Volume: 31
Issue: 11
Pages: 2479-2490
Publication
First Author: Stevenson AJ
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Multiscale imaging of basal cell dynamics in the functionally mature mammary gland.
Volume: 117
Issue: 43
Pages: 26822-26832
Publication    
First Author: Tworig JM
Year: 2021
Journal: Elife
Title: Excitatory neurotransmission activates compartmentalized calcium transients in Müller glia without affecting lateral process motility.
Volume: 10
Publication
First Author: Mora AL
Year: 2003
Journal: Cell Death Differ
Title: Antiapoptotic function of NF-kappaB in T lymphocytes is influenced by their differentiation status: roles of Fas, c-FLIP, and Bcl-xL.
Volume: 10
Issue: 9
Pages: 1032-44
Protein
Organism: Mus musculus/domesticus
Length: 802  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 457  
Fragment?: false