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Search results 2701 to 2800 out of 2902 for Pdx1

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Type Details Score
Publication
18515092 | J:141804
First Author: Fendrich V
Year: 2008
Journal: Gastroenterology
Title: Hedgehog signaling is required for effective regeneration of exocrine pancreas.
Volume: 135
Issue: 2
Pages: 621-31
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Publication
25878147 | J:220300
First Author: Massó-Vallés D
Year: 2015
Journal: Cancer Res
Title: Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma.
Volume: 75
Issue: 8
Pages: 1675-81
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Publication
34188043 | J:307917
First Author: Isermann T
Year: 2021
Journal: Nat Commun
Title: Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity.
Volume: 12
Issue: 1
Pages: 4019
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Publication
26243191 | J:260386
First Author: Foley K
Year: 2015
Journal: Sci Signal
Title: Semaphorin 3D autocrine signaling mediates the metastatic role of annexin A2 in pancreatic cancer.
Volume: 8
Issue: 388
Pages: ra77
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Publication
36271032 | J:331742
First Author: Lakshmanan I
Year: 2022
Journal: Oncogene
Title: Muc16 depletion diminishes KRAS-induced tumorigenesis and metastasis by altering tumor microenvironment factors in pancreatic ductal adenocarcinoma.
Volume: 41
Issue: 48
Pages: 5147-5159
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Publication
22220202 | J:182325
First Author: Colvin EK
Year: 2011
Journal: PLoS One
Title: Retinoid signaling in pancreatic cancer, injury and regeneration.
Volume: 6
Issue: 12
Pages: e29075
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Publication
35212370 | J:325481
First Author: Schniers BK
Year: 2022
Journal: Biochem J
Title: Deletion of Slc6a14 reduces cancer growth and metastatic spread and improves survival in KPC mouse model of spontaneous pancreatic cancer.
Volume: 479
Issue: 5
Pages: 719-730
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Publication
36256464 | J:332123
 
First Author: Dixit A
Year: 2022
Journal: JCI Insight
Title: Targeting TNF-α-producing macrophages activates antitumor immunity in pancreatic cancer via IL-33 signaling.
Volume: 7
Issue: 22
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Publication
29596465 | J:261064
First Author: Germino EA
Year: 2018
Journal: PLoS One
Title: Homozygous KSR1 deletion attenuates morbidity but does not prevent tumor development in a mouse model of RAS-driven pancreatic cancer.
Volume: 13
Issue: 3
Pages: e0194998
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Publication
29809170 | J:265680
First Author: Yamaguchi J
Year: 2018
Journal: J Clin Invest
Title: Trefoil factor 1 inhibits epithelial-mesenchymal transition of pancreatic intraepithelial neoplasm.
Volume: 128
Issue: 8
Pages: 3619-3629
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Publication
21266354 | J:169401
First Author: Timpson P
Year: 2011
Journal: Cancer Res
Title: Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53.
Volume: 71
Issue: 3
Pages: 747-57
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Genotype
Genotype
Symbol: Myt1/Myt1 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * CBA * CD-1 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca2/Brca2 Kras/Kras<+> Trp53/Trp53<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca2/Brca2 Kras/Kras<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Pten/Pten<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Pten/Pten Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a<+> Kras/Kras<+> Trp53/Trp53 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Kras/Kras<+> Trp53/Trp53 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a<+> Kras/Kras<+> Trp53/Trp53<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Kras/Kras<+> Trp53/Trp53<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre)6Tuv/? TgTn(sb-T2/Onc)#Dla/?
Background: involves: 129S4/SvJae * 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca1/Brca1 Kras/Kras<+> Trp53/Trp53 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca1/Brca1 Kras/Kras<+> Trp53/Trp53 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/? Tg(Pdx1-cre)6Tuv/? Tg(tetO-MYC)36Bop/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a<+> Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/? Tg(Pdx1-cre)6Tuv/? Tg(tetO-MYC)36Bop/?
Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cish/Cish Tg(Ins1-EGFP)1Hara/? Tg(Pdx1-cre)89.1Dam/?
Background: involves: C57BL/6 * CBA * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(CAG-Bgeo,-tsA58T)T26Ichi/? Tg(Pdx1-cre)6Tuv/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/? Tg(Pdx1-cre)6Tuv/?
Background: B6.Cg-Gt(ROSA)26Sor Tg(Pdx1-cre)6Tuv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Rab11fip1/Rab11fip1 Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Epha2/Epha2 Kras/Kras<+> Trp53/Trp53<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S/SvEv * 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Prdm1/Prdm1 Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129 * C57BL/6NCrl * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129 * C57BL/6NCrl * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd9/Cd9<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53
Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdk8/Cdk8 Tg(Pdx1-cre)6Tuv/?
Background: involves: C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gata4/Gata4 Gata6/Gata6 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dpy30/Dpy30 Tg(Pdx1-cre)89.1Dam/?
Background: involves: C57BL/6 * C57BL/6N * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-flpo)#Ybi/?
Background: involves: 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
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Publication
18288891 | J:135659
First Author: Tanabe K
Year: 2008
Journal: PLoS Biol
Title: Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance.
Volume: 6
Issue: 2
Pages: e37
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Publication
31055616 | J:282688
First Author: Obata A
Year: 2019
Journal: Diabetologia
Title: Vascular endothelial PDPK1 plays a pivotal role in the maintenance of pancreatic beta cell mass and function in adult male mice.
Volume: 62
Issue: 7
Pages: 1225-1236
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Publication
35802167 | J:331554
First Author: Habibe JJ
Year: 2022
Journal: Diabetologia
Title: Glucose-mediated insulin secretion is improved in FHL2-deficient mice and elevated FHL2 expression in humans is associated with type 2 diabetes.
Volume: 65
Issue: 10
Pages: 1721-1733
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Publication
23958541 | J:324563
First Author: Philip B
Year: 2013
Journal: Gastroenterology
Title: A high-fat diet activates oncogenic Kras and COX2 to induce development of pancreatic ductal adenocarcinoma in mice.
Volume: 145
Issue: 6
Pages: 1449-58
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Publication
27076077 | J:235402
First Author: Yoshihara E
Year: 2016
Journal: Cell Metab
Title: ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β Cells.
Volume: 23
Issue: 4
Pages: 622-34
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Publication
21747171 | J:176160
First Author: Tiano JP
Year: 2011
Journal: J Clin Invest
Title: Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes.
Volume: 121
Issue: 8
Pages: 3331-42
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Publication
28790031 | J:245611
First Author: Chiou SH
Year: 2017
Journal: Cancer Discov
Title: BLIMP1 Induces Transient Metastatic Heterogeneity in Pancreatic Cancer.
Volume: 7
Issue: 10
Pages: 1184-1199
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Publication
31162144 | J:285966
 
First Author: Markosyan N
Year: 2019
Journal: J Clin Invest
Title: Tumor cell-intrinsic EPHA2 suppresses anti-tumor immunity by regulating PTGS2 (COX-2).
Volume: 130
Pages: 3594-3609
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Publication
30456390 | J:287931
First Author: Pitarresi JR
Year: 2018
Journal: Life Sci Alliance
Title: Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth.
Volume: 1
Issue: 5
Pages: e201800190
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Publication
24794439 | J:211801
First Author: Kinsey C
Year: 2014
Journal: Cell Rep
Title: Plac8 links oncogenic mutations to regulation of autophagy and is critical to pancreatic cancer progression.
Volume: 7
Issue: 4
Pages: 1143-55
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Publication
23361300 | J:196881
First Author: Khalaileh A
Year: 2013
Journal: Cancer Res
Title: Phosphorylation of ribosomal protein S6 attenuates DNA damage and tumor suppression during development of pancreatic cancer.
Volume: 73
Issue: 6
Pages: 1811-20
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Publication
32200350 | J:288996
First Author: Muthalagu N
Year: 2020
Journal: Cancer Discov
Title: Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal Adenocarcinoma.
Volume: 10
Issue: 6
Pages: 872-887
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Publication
20624967 | J:162569
First Author: Mazur PK
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma.
Volume: 107
Issue: 30
Pages: 13438-43
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Publication
24216479 | J:204180
First Author: Court H
Year: 2013
Journal: J Clin Invest
Title: Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression.
Volume: 123
Issue: 11
Pages: 4681-94
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Publication
25306215 | J:217168
 
First Author: Stellas D
Year: 2014
Journal: J Natl Cancer Inst
Title: Therapeutic effects of an anti-Myc drug on mouse pancreatic cancer.
Volume: 106
Issue: 12
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Publication
29249692 | J:253745
First Author: Renz BW
Year: 2018
Journal: Cancer Cell
Title: β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.
Volume: 33
Issue: 1
Pages: 75-90.e7
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Publication
27825441 | J:237506
First Author: Houtz J
Year: 2016
Journal: Dev Cell
Title: Neurotrophin Signaling Is Required for Glucose-Induced Insulin Secretion.
Volume: 39
Issue: 3
Pages: 329-345
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Publication
30705405 | J:278756
First Author: Nishikawa Y
Year: 2019
Journal: Oncogene
Title: Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis.
Volume: 38
Issue: 22
Pages: 4283-4296
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Publication
26203139 | J:225811
First Author: Kim ER
Year: 2015
Journal: J Neurosci
Title: Hypothalamic Non-AgRP, Non-POMC GABAergic Neurons Are Required for Postweaning Feeding and NPY Hyperphagia.
Volume: 35
Issue: 29
Pages: 10440-50
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Publication
25716832 | J:219852
First Author: Wu Z
Year: 2015
Journal: J Neurosci
Title: GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding.
Volume: 35
Issue: 8
Pages: 3312-8
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Publication
24721715 | J:213751
First Author: Baumgartner BK
Year: 2014
Journal: Dev Biol
Title: Distinct requirements for beta-catenin in pancreatic epithelial growth and patterning.
Volume: 391
Issue: 1
Pages: 89-98
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Publication
18442046 | J:136227
First Author: Elghazi L
Year: 2008
Journal: Genesis
Title: Generation of a reporter mouse line expressing Akt and EGFP upon Cre-mediated recombination.
Volume: 46
Issue: 5
Pages: 256-64
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Publication
25133424 | J:215828
First Author: Chamberlain CE
Year: 2014
Journal: J Clin Invest
Title: Menin determines K-RAS proliferative outputs in endocrine cells.
Volume: 124
Issue: 9
Pages: 4093-101
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Publication
25024225 | J:212242
First Author: Lee JJ
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Stromal response to Hedgehog signaling restrains pancreatic cancer progression.
Volume: 111
Issue: 30
Pages: E3091-100
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Publication
26560028 | J:244297
First Author: Zheng X
Year: 2015
Journal: Nature
Title: Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer.
Volume: 527
Issue: 7579
Pages: 525-530
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Publication
29364867 | J:257934
First Author: Mueller S
Year: 2018
Journal: Nature
Title: Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.
Volume: 554
Issue: 7690
Pages: 62-68
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Publication
25119024 | J:217085
First Author: Viale A
Year: 2014
Journal: Nature
Title: Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.
Volume: 514
Issue: 7524
Pages: 628-32
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Publication
26153246 | J:263296
First Author: Oropeza D
Year: 2015
Journal: Diabetes
Title: Phenotypic Characterization of MIP-CreERT1Lphi Mice With Transgene-Driven Islet Expression of Human Growth Hormone.
Volume: 64
Issue: 11
Pages: 3798-807
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Publication
26567136 | J:237566
First Author: Baird JR
Year: 2016
Journal: Cancer Res
Title: Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors.
Volume: 76
Issue: 1
Pages: 50-61
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Publication
25127677 | J:314626
First Author: Hermann PC
Year: 2014
Journal: Gastroenterology
Title: Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
Volume: 147
Issue: 5
Pages: 1119-33.e4
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Publication
37102225 | J:335178
First Author: Gams A
Year: 2023
Journal: Physiol Rep
Title: Evidence of sex differences in cancer-related cardiac complications in mouse models of pancreatic and liver cancer.
Volume: 11
Issue: 8
Pages: e15672
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Publication
30228296 | J:283080
First Author: Chiou SH
Year: 2018
Journal: Sci Rep
Title: Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance.
Volume: 8
Issue: 1
Pages: 14008
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Publication
22699621 | J:186717
First Author: Pérez-Mancera PA
Year: 2012
Journal: Nature
Title: The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.
Volume: 486
Issue: 7402
Pages: 266-70
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Publication
20614471 | J:164701
First Author: Carpenter AC
Year: 2010
Journal: Genesis
Title: Generation of mice with a conditional null allele for Wntless.
Volume: 48
Issue: 9
Pages: 554-8
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Publication
33307028 | J:308020
First Author: Peran I
Year: 2021
Journal: Gastroenterology
Title: Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice.
Volume: 160
Issue: 4
Pages: 1359-1372.e13
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Publication
30877201 | J:277840
First Author: Corsa CAS
Year: 2019
Journal: J Biol Chem
Title: The E3 ubiquitin ligase parkin is dispensable for metabolic homeostasis in murine pancreatic β cells and adipocytes.
Volume: 294
Issue: 18
Pages: 7296-7307
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Publication
35418690 | J:324774
First Author: Kidger AM
Year: 2022
Journal: Oncogene
Title: Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6.
Volume: 41
Issue: 20
Pages: 2811-2823
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Publication
30858608 | J:285667
First Author: Liko D
Year: 2019
Journal: Cell Death Differ
Title: Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas.
Volume: 26
Issue: 12
Pages: 2535-2550
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Publication
32234521 | J:336882
First Author: Ruscetti M
Year: 2020
Journal: Cell
Title: Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.
Volume: 181
Issue: 2
Pages: 424-441.e21
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Publication
31116975 | J:284493
First Author: Sharon N
Year: 2019
Journal: Cell Rep
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