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Search results 101 to 200 out of 725 for Ttk

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Type Details Score
Allele
Name: Ttk protein kinase; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
UniProt Feature
Begin: 1
Description: Dual specificity protein kinase TTK
Type: chain
End: 856
Protein
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 773  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 856  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 830  
Fragment?: false
Allele    
Name: Ttk protein kinase; wild type
Allele  
Name: Ttk protein kinase; gene trap YTA024, BayGenomics
Allele Type: Gene trapped
Allele
Name: Ttk protein kinase; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele  
Name: Ttk protein kinase; gene trap EUCE0168a08, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Allele
Name: Ttk protein kinase; targeted mutation 1, Katja Wassmann
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele  
Name: Ttk protein kinase; gene trap P019C03, German Gene Trap Consortium
Allele Type: Gene trapped
Allele
Name: Ttk protein kinase; targeted mutation 2.1, Geert Kops
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence
Allele  
Name: Ttk protein kinase; gene trap AT0190, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
Allele  
Name: Ttk protein kinase; gene trap OST114871, Lexicon Genetics
Allele Type: Gene trapped
Allele
Name: Ttk protein kinase; targeted mutation 1.1, Geert Kops
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence
Allele  
Name: Ttk protein kinase; gene trap OST196894, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: Ttk protein kinase; gene trap AR0284, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele  
Name: Ttk protein kinase; gene trap A023E04, German Gene Trap Consortium
Allele Type: Gene trapped
Allele
Name: Ttk protein kinase; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Allele  
Name: Ttk protein kinase; gene trap OST194061, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: Ttk protein kinase; gene trap OST147691, Lexicon Genetics
Allele Type: Gene trapped
Allele
Name: Ttk protein kinase; endonuclease-mediated mutation 11, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele  
Name: Ttk protein kinase; gene trap G042B10, German Gene Trap Consortium
Allele Type: Gene trapped
Allele
Name: Ttk protein kinase; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Allele  
Name: Ttk protein kinase; gene trap OST220006, Lexicon Genetics
Allele Type: Gene trapped
Genotype
Symbol: Ttk/Ttk
Background: C57BL/6NJ-Ttk/Mmjax
Zygosity: hm
Has Mutant Allele: true
Strain
Attribute String: targeted mutation, mutant strain, congenic
Allele  
Name: Ttk protein kinase; gene trap IST14387E12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Ttk protein kinase; gene trap IST14419E4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Strain
Attribute String: congenic, mutant strain, targeted mutation
Allele  
Name: Ttk protein kinase; gene trap 80B8, Centre for Modeling Human Disease
Allele Type: Gene trapped
Allele  
Name: Ttk protein kinase; gene trap 435F6, Centre for Modeling Human Disease
Allele Type: Gene trapped
Strain
Attribute String: mutant stock, gene trap
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Genotype
Symbol: Tg(Zp3-cre)93Knw/? Ttk/Ttk
Background: involves: 129 * C57BL/6 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
GO Term
GO Term
Publication
First Author: Tomizawa K
Year: 2001
Journal: FEBS Lett
Title: Tau-tubulin kinase phosphorylates tau at Ser-208 and Ser-210, sites found in paired helical filament-tau.
Volume: 492
Issue: 3
Pages: 221-7
Publication
First Author: Iida R
Year: 2010
Journal: Mol Cell Biol
Title: A novel transcriptional repressor, Rhit, is involved in heat-inducible and age-dependent expression of Mpv17-like protein, a participant in reactive oxygen species metabolism.
Volume: 30
Issue: 10
Pages: 2306-15
Protein Domain
Type: Family
Description: This family includes ORF A55R from Vaccinia virus, which is characterised by having a BTB (for BR-C, ttk and bab) []or POZ (for Pox virus and Zinc finger) []domain near the N terminus. The proteins are also characterised by kelch repeats C-terminal to the BTB domain. The function of these proteins are unknown.
GO Term
GO Term
Publication
First Author: Bardwell VJ
Year: 1994
Journal: Genes Dev
Title: The POZ domain: a conserved protein-protein interaction motif.
Volume: 8
Issue: 14
Pages: 1664-77
Publication
First Author: Zollman S
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila.
Volume: 91
Issue: 22
Pages: 10717-21
Protein
Organism: Mus musculus/domesticus
Length: 522  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 210  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 44  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 506  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 274  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 42  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 72  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: false
Publication
First Author: Deweindt C
Year: 1995
Journal: Cell Growth Differ
Title: The LAZ3/BCL6 oncogene encodes a sequence-specific transcriptional inhibitor: a novel function for the BTB/POZ domain as an autonomous repressing domain.
Volume: 6
Issue: 12
Pages: 1495-503
Publication
First Author: Wong CW
Year: 1998
Journal: J Biol Chem
Title: Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARalpha, and BCL-6.
Volume: 273
Issue: 42
Pages: 27695-702
Publication
First Author: Huynh KD
Year: 1998
Journal: Oncogene
Title: The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT.
Volume: 17
Issue: 19
Pages: 2473-84
Publication
First Author: Costoya JA
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: Functional analysis of the role of POK transcriptional repressors.
Volume: 6
Issue: 1
Pages: 8-18
Publication
First Author: Aravind L
Year: 1999
Journal: J Mol Biol
Title: Fold prediction and evolutionary analysis of the POZ domain: structural and evolutionary relationship with the potassium channel tetramerization domain.
Volume: 285
Issue: 4
Pages: 1353-61
Protein Domain
Type: Homologous_superfamily
Description: The BTB (for BR-C, ttk and bab) []or POZ (for Pox virus and Zinc finger) [, ]domain is a versatile protein-protein interaction motif involved in many cellular functions, including transcriptional regulation, cytoskeleton dynamics, ion channel assembly and gating, and targeting proteins for ubiquitination []. The BTB domain can occur alongside other domains: BTB-zinc finger (BTB-ZF), BTB-BACK-Kelch (BBK), voltage-gated potassium channel T1 (T1-Kv) [], MATH-BTB, BTB-NPH3 and BTB-BACK-PHR (BBP). Other proteins, such as Skp1 and ElonginC, consist almost exclusively of the core BTB fold. In all of these protein families, the BTB core fold is structurally conserved, consisting of a 2-layer alpha/beta topology where a cluster of alpha helices is flanked by short β-sheets []. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [, , ]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.This entry includes the BTB/POZ domain, as well as Skp1 N-terminal region which has an α/β structure similar to that of the BTB/POZ domain fold [, ].
Protein
Organism: Mus musculus/domesticus
Length: 723  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 927  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 56  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 43  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 60  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 161  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 40  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 310  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 184  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 50  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 51  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 71  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 62  
Fragment?: true